Intrahepatic Fat Content and Markers of Hepatic Fibrosis in Obese Children
Table 2
Comparison of biochemical parameters.
Parameters
SOB ( = 75)
SS ( = 49)
NASH ( = 65)
ALT (U/L)
18 (14–23) (4–114)
37 (29.5–43.5) (17–50)
96 (69.5–137) (51–370)
AST (U/L)
23 (20–26) (12–74)
28 (24.5–32) (18–102)
51 (41–75.5) (27–293)
γ-GT (U/L)
16 (13–21) (7–71)
23 (19.5–28) (2–71)
42 (28.5–65) (17–138)
TG (mmol/L)
0.95 (0.82–1.39) (0.39–3.69)
1.33 (0.94–1.77) (0.4–3.86)
1.43 (0.93–1.80) (0.65–4.69)
CHOL (mmol/L)
4.28 ± 0.71 (3.09–6.25)
4.32 ± 0.86 (2.54–6.55)
4.59 ± 0.98 (1.14–7.73)
HDL (mmol/L)
1.27 ± 0.37 (0.77–2.71)
1.17 ± 0.31 (0.58–1.79)
1.05 ± 2.63 (0.57–1.66)
LDL (mmol/L)
2.32 ± 0.53 (1.07–3.91)
2.44 ± 0.64 (1.19–4.09)
2.61 ± 0.55 (1.3–3.85)
Uric acid (µmol/L)
346.02 ± 80.3 (201.9–586.4)
392.14 ± 74.05 (253.1–568.5)
429.38 ± 90.72 (226.7–673.6)
HA (ng/mL)
59.56 (40.22–81.6) (16–183)
60.14 (49.7–88.53) (9–130)
71.7 (53.04–94.02) (16–166)
CIV (ng/mL)
78.79 ± 27.77 (48–135)
82.20 ± 32.40 (53–118)
85.49 ± 27.76 (46–132)
PCIII (ng/mL)
173.14 (133.94–217.14) (73–299)
161.5 (138.44–198.20) (81–368)
195.1 (153.75–258.58) (106–462)
LN (ng/mL)
128.90 ± 21.17 (67–195)
128.99 ± 17.55 (73–178)
126.34 ± 30.71 (14–214)
NFS
−5.57 ± 1.34 (−7.94–−1.11)
−5.50 ± 1.33 (−8.63–−0.94)
−5.29 ± 1.23 (−6.45–−0.32)
APRI
0.125 (0.10–0.16) (0.06–0.41)
0.16 (0.14–0.18) (0.08–0.7)
0.33 (0.23–0.45) (0.15–1.78)
FIB-4
0.17 (0.12–0.23) (0.08–0.56)
0.15 (0.13–0.17) (0.07–0.71)
0.19 (0.16–0.26) (0.07–0.64)
HbA1c (%)
5.76 ± 0.41 (4.9–7.0)
5.90 ± 0.49 (4.8–6.9)
5.85 ± 0.39 (4.9–6.8)
Insulin 0 (µIU/mL)
16.10 (12.38–22.38) (0.8–46.1)
19.9 (13.85–31.15) (1.3–64.3)
21.60 (14.40–30.30) (0.9–56.9)
Insulin 120 (µIU/mL)
53.10 (30.10–81.40) (1.9–174.2)
73.10 (29.15–119.85) (2.4–300)
78.80 (29.50–144.65) (2.1–300)
OGTT 120 (mmol/L)
6.50 (5.10–11.10) (5.1–11.1)
6.70 (6025–7.40) (5.4–10)
7.30 (6.40–7.90) (5–18.8)
FG (mmol/L)
5.40 (5.10–5.70) (4.3–7.7)
5.40 (4.40–8.90) (4.4–8.9)
5.50 (5.25–5.75) (4.1–8)
HOMA-IR
3.79 (2.85–5.08) (0.18–10.65)
4.77 (3.37–7.06) (0.31–24.29)
5.03 (3.58–7.48) (0.23–15.17)
Compared with SOB, and ; compared to SS, and . Quantitative data with normal distribution are expressed as the mean ± SD, and variables with skewed distribution are presented as median with interquartile range. The ranges of all the parameters were listed in the bracket.