Research Article

GC Gene Polymorphisms and Vitamin D-Binding Protein Levels Are Related to the Risk of Generalized Aggressive Periodontitis

Table 3

Haplotype analysis of GC rs17467825, rs4588, and rs7041 polymorphisms and their association with generalized aggressive periodontitis.

HaplotypesHaplotype frequencyOR (95% CI)Adjusted
rs17467825rs4588TotalGroup HPGroup AgP

1AC0.66640.65090.67191
2GA0.31610.32580.31270.95 (0.70–1.28)0.74
3GC0.01120.02340.00690.29 (0.09–0.96)0.043
4AA0.00620.0084NA

AgP: aggressive periodontitis; HP: healthy participant; OR: odds ratio; 95% CI: 95% confidence interval; NA: not analyzed; adjusted : adjusted by age and gender; : statistical significance.