The Roles of PI3K/AKT/mTOR and MAPK/ERK Signaling Pathways in Human Pheochromocytomas

Figure 3

Effect of pathway inhibitors on cell proliferation in human PPGL cells. Experiments were performed in four independent wells for each group () and repeated in ten PPGLs (). The results were represented in the scatter diagram (a) and column chart (b). versus control group; versus LY294002 group; versus U0126 group. N: PPGL without gene mutation of SDHB, SDHC, SDHD, VHL, and RET; B: PPGL with SDHB mutation; D: PPGL with SDHD mutation; R: PPGL with RET mutation.

(a)

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