Research Article

Midkine: A Novel Biomarker to Predict Malignancy in Patients with Nodular Thyroid Disease

Table 1

Demographic and clinical characteristics in relation to serum midkine (SMK) and nodular midkine (NMK) concentrations.

Demographic and clinical characteristicsSMKNMK

Gender
 Female0.600.52
 Male0.63 (0.30–4.97)0.68 (0.35–1.73)
0.9120.223
Age (years)
 <400.67 (0.37–4.97)0.56 (0.38–1.73)
 40–590.60 (0.30–2.77)0.52 (0.35–1.45)
 ≥600.60 (0.40–2.03)0.55 (0.37–0.82)
0.3960.298
TSH (µIU/mL)
 <0.40.57 (0.33–2.03)0.52 (0.35–0.82)
 0.4–40.63 (0.30–4.97)0.53 (0.35–1.73)
 >40.63 (0.50–1.37)0.58 (0.43–0.62)
0.4670.529

BMI: body mass index; TSH: thyroid stimulating hormone.