Table of Contents Author Guidelines Submit a Manuscript
International Journal of Endocrinology
Volume 2016 (2016), Article ID 6218437, 7 pages
http://dx.doi.org/10.1155/2016/6218437
Research Article

Body Composition in Adult Patients with Thalassemia Major

1Department of Radiology, University Hospital of Larissa, Medical School of Thessaly, Larissa, Greece
2Department of Radiology, General Hospital of Larissa, Greece

Received 14 May 2016; Accepted 7 August 2016

Academic Editor: Michael Horowitz

Copyright © 2016 Marianna Vlychou et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. R. Galanello and R. Origa, “Beta-thalassemia,” Orphanet Journal of Rare Diseases, vol. 5, no. 1, article 11, 2010. View at Publisher · View at Google Scholar · View at Scopus
  2. E. A. Rachmilewitz and P. J. Giardina, “How I treat thalassemia,” Blood, vol. 118, no. 13, pp. 3479–3488, 2011. View at Publisher · View at Google Scholar · View at Scopus
  3. A. A. Shamshirsaz, M. R. Bekheirnia, M. Kamgar et al., “Metabolic and endocrinologic complications in beta-thalassemia major: a multicenter study in Tehran,” BMC Endocrine Disorders, vol. 3, article 4, 2003. View at Publisher · View at Google Scholar · View at Scopus
  4. E. Carmina, G. Di Fede, N. Napoli et al., “Hypogonadism and hormone replacement therapy on bone mass of adult women with thalassemia major,” Calcified Tissue International, vol. 74, no. 1, pp. 68–71, 2004. View at Publisher · View at Google Scholar · View at Scopus
  5. M. R. Gamberini, V. de Sanctis, and G. Gilli, “Hypogonadism, diabetes mellitus, hypothyroidism, hypoparathyroidism: incidence and prevalence related to iron overload and chelation therapy in patients with thalassaemia major followed from 1980 to 2007 in the Ferrara centre,” Pediatric Endocrinology Reviews, vol. 6, supplement 1, pp. 158–169, 2008. View at Google Scholar · View at Scopus
  6. M. Toumba, A. Sergis, C. Kanaris, and N. Skordis, “Endocrine complications in patients with thalassaemia major,” Pediatric Endocrinology Reviews, vol. 5, no. 2, pp. 642–648, 2007. View at Google Scholar · View at Scopus
  7. V. De Sanctis, A. T. Soliman, H. Elsedfy et al., “Growth and endocrine disorders in thalassemia: the international network on endocrine complications in thalassemia (I-CET) position statement and guidelines,” Indian Journal of Endocrinology and Metabolism, vol. 17, no. 1, pp. 8–18, 2013. View at Publisher · View at Google Scholar
  8. A. T. Soliman, N. El Banna, M. Abdel Fattah, M. M. ElZalabani, and B. M. Ansari, “Bone mineral density in prepubertal children with β-thalassemia: correlation with growth and hormonal data,” Metabolism: Clinical and Experimental, vol. 47, no. 5, pp. 541–548, 1998. View at Publisher · View at Google Scholar · View at Scopus
  9. F. Mohseni, M. R. Mohajeri-Tehrani, B. Larijani, and Z. Hamidi, “Relation between BMD and biochemical, transfusion and endocrinological parameters in pediatric thalassemic patients,” Archives of Osteoporosis, vol. 9, article 174, 2014. View at Publisher · View at Google Scholar · View at Scopus
  10. G. J. Fuchs, P. Tienboon, M. A. Khaled et al., “Nutritional support and growth in thalassaemia major,” Archives of Disease in Childhood, vol. 76, no. 6, pp. 509–512, 1997. View at Publisher · View at Google Scholar · View at Scopus
  11. N. Saki, S. Abroun, F. Salari, F. Rahim, M. Shahjahani, and J. Mohammadi-Asl, “Molecular aspects of bone resorption in β-thalassemia major,” Cell Journal, vol. 17, no. 2, pp. 193–200, 2015. View at Google Scholar · View at Scopus
  12. M. Casale, S. Citarella, A. Filosa et al., “Endocrine function and bone disease during long-term chelation therapy with deferasirox in patients with β-thalassemia major,” American Journal of Hematology, vol. 89, no. 12, pp. 1102–1106, 2014. View at Publisher · View at Google Scholar · View at Scopus
  13. M. Baldini, S. Forti, A. Marcon et al., “Endocrine and bone disease in appropriately treated adult patients with beta-thalassemia major,” Annals of Hematology, vol. 89, no. 12, pp. 1207–1213, 2010. View at Publisher · View at Google Scholar · View at Scopus
  14. C. J. Rosen and A. Klibanski, “Bone, fat, and body composition: evolving concepts in the pathogenesis of osteoporosis,” The American Journal of Medicine, vol. 122, no. 5, pp. 409–414, 2009. View at Publisher · View at Google Scholar · View at Scopus
  15. A. Andreoli, G. Scalzo, S. Masala, U. Tarantino, and G. Guglielmi, “Body composition assessment by dual-energy X-ray absorptiometry (DXA),” Radiologia Medica, vol. 114, no. 2, pp. 286–300, 2009. View at Publisher · View at Google Scholar · View at Scopus
  16. M. G. Vogiatzi, E. A. Macklin, E. B. Fung et al., “Bone disease in Thalassemia: a frequent and still unresolved problem,” Journal of Bone and Mineral Research, vol. 24, no. 3, pp. 543–557, 2009. View at Publisher · View at Google Scholar · View at Scopus
  17. D. L. Kendler, J. L. C. Borges, R. A. Fielding et al., “The official positions of the International Society for Clinical Densitometry: indications of use and reporting of DXA for body composition,” Journal of Clinical Densitometry, vol. 16, no. 4, pp. 496–507, 2013. View at Publisher · View at Google Scholar · View at Scopus
  18. M. A. Laskey, “Dual-energy X-ray absorptiometry and body composition,” Nutrition, vol. 12, no. 1, pp. 45–51, 1996. View at Publisher · View at Google Scholar · View at Scopus
  19. V. Benetou, C. Bamia, D. Trichopoulos, and A. Trichopoulou, “Associations of anthropometric characteristics with blood cholesterol fractions among adults. The Greek EPIC study,” European Journal of Clinical Nutrition, vol. 60, no. 8, pp. 942–948, 2006. View at Publisher · View at Google Scholar · View at Scopus
  20. J. Kalef-Ezra, A. Zibis, N. Chaliassos, I. Hatzikonstantinou, and A. Karantanas, “Body composition in homozygous β-thalassemia,” Annals of the New York Academy of Sciences, vol. 904, pp. 621–624, 2000. View at Google Scholar · View at Scopus
  21. E. B. Fung, Y. Xu, J. L. Kwiatkowski et al., “Relationship between chronic transfusion therapy and body composition in subjects with thalassemia,” Journal of Pediatrics, vol. 157, no. 4, pp. 641–647.e2, 2010. View at Publisher · View at Google Scholar · View at Scopus
  22. P. Wong, P. J. Fuller, M. T. Gillespie et al., “The effect of gonadal status on body composition and bone mineral density in transfusion-dependent thalassemia,” Osteoporosis International, vol. 25, no. 2, pp. 597–604, 2014. View at Publisher · View at Google Scholar · View at Scopus
  23. M. H. Gozashti, A. Hasanzadeh, and M. Mashrouteh, “Prevalence of metabolic syndrome in patients with minor beta thalassemia and its related factors: a cross-sectional study,” Journal of Diabetes & Metabolic Disorders, vol. 13, article 108, 2014. View at Publisher · View at Google Scholar
  24. A. I. Triantafyllou, G. P. Vyssoulis, E. A. Karpanou et al., “Impact of β-thalassemia trait carrier state on cardiovascular risk factors and metabolic profile in patients with newly diagnosed hypertension,” Journal of Human Hypertension, vol. 28, no. 5, pp. 328–332, 2014. View at Publisher · View at Google Scholar · View at Scopus
  25. E. B. Fung, E. P. Vichinsky, J. L. Kwiatkowski et al., “Characterization of low bone mass in young patients with thalassemia by DXA, pQCT and markers of bone turnover,” Bone, vol. 48, no. 6, pp. 1305–1312, 2011. View at Publisher · View at Google Scholar · View at Scopus