Research Article

The Frequency of Langerhans Islets β-Cells Autoantibodies (Anti-GAD) in Georgian Children and Adolescents with Chronic Autoimmune Thyroiditis

Table 1

Clinical characteristics of 41 patients aged 6 to 16 with autoimmune thyroiditis and the control group.

Total
Females/malesTSH µIU/mL
median (range)
Anti-TPO IU/mL median (range)Anti-TG IU/mL
median (range)

Primary hypothyroidism (without goiter)33/074.89 (11.57–137.42)156.9 (153.13–318.05)342.69 (217.01–375.21)
Subclinical hypothyroidism (without goiter)64/25.28 (5.12–7.36)239.59 (78.07–569.56)379.84 (82.7–482.35)
Primary hypothyroidism with diffuse goiter54/137.45 (15.24–150.01)480.27 (206–653.38)
Subclinical hypothyroidism with diffuse goiter2115/64.98 (4.43–6.28)211.57 (72.95–517.32)292.19 (136.47–546.24)
Primary hypothyroidism with nodular goiter11/094.78517.32
Subclinical hypothyroidism with nodular goiter43/14.88 (4.67–4.99)243.98 (145.22–526.75)619.53 (214.15–1024.91)
Diffuse goiter with hyperthyroidism11/00.01238.78
Levothyroxine treatment3727/105.46 (4.43–150.01)216.35 (72.95–653.38)333.42 (82.7–1024.91)
All patients 4131/105.26 (0.01–150.01)236.35 (72.95–653.38)333.42 (82.7–1024.91)
Control group5134/171.84 (0.53–3.78)36.91 (25.02–51.35)39.85 (29.76–52.06)

Including all patients from all subgroups which receive levothyroxine treatment.