Long-Term Quality of Life and Pregnancy Outcomes of Differentiated Thyroid Cancer Survivors Treated by Total Thyroidectomy and I¹³¹ during Adolescence and Young Adulthood

Table 3

Pregnancy outcomes after administration of I¹³¹ in subjects diagnosed with differentiated thyroid cancer before age of 25 years.

	Cumulative dose of I^131
	≤3.85 GBq; ()	>3.85 GBq; ()
Maternal age at pregnancy (yrs)	26.3 ± 5.1	27.3 ± 2.4
Interval between I^131 and pregnancy (months)	69.7 ± 47.8	75.3 ± 64.8
Cumulative dose of I^131 before pregnancy^†	3.74 ± 0.08^†	7.88 ± 1.3^†
Intention to have children
Patients already having children	6	15
Patients without children	12	12
Fertility problems after I^131
Pregnancy after intrauterine insemination	2	0
Pregnancy after FIV ICSI	1 (ongoing)	0
Dysovulation	0	1
Pregnancy outcomes
Voluntary abortion	0	0
Miscarriage during the first trimester	1	5
Medical abortion	0	1
Live births	9	24
Birth term (weeks)	40 ± 1.2	38.7 ± 2.4
Birth weight (g)	3.256 ± 0.2	3.116 ± 0.6
Gender (male)	5	15
Number of patients having children	6	15
Number of children after I^131	9	24

: number of subjects. Data are presented as mean (±SD) or number (percentage).
^†.