Effect on Insulin-Stimulated Release of D-Chiro-Inositol-Containing Inositolphosphoglycan Mediator during Weight Loss in Obese Women with and without Polycystic Ovary Syndrome
Table 2
Changes in metabolic parameters after 8 weeks of weight loss intervention in women with and without PCOS.
Parameter
PCOS ()
Control ()
value
Weight (kg)
−4.08 (−2.13, −6.02)
−4.69 (−2.89, −6.49)
0.6281
BMI (kg/m2)
−1.46 (−0.72, −2.20)
−1.80 (−1.14, −2.45)
0.4829
Waist/hip ratio
−0.014 (−0.034, 0.006)
−0.040 (−0.107, 0.027)
0.3878
Fasting insulin (mg/dL)
+1.8 (−2.2, +5.7)
−5.0 (−10.6, +0.6)
0.0625
Fasting glucose (mg/dL)
−1.15 (−4.43, +2.13)
+0.21 (−2.35, +2.77)
0.5041
AUC insulin (min⋅mg/dL)
−1009 (−2601, +642)
−1403 (−2886, −80)
0.1961
AUC glucose (min⋅mg/dL)
−961 (−1944, +21)
+152.8 (−1245, +1550)
0.1600
Matsuda index
+0.17 (−0.87, +1.21)
+2.60 (+0.38, +5.58)
0.1168
AUC DCI-IPG (% min)
−446 (−4078, +3185)
−3754 (−11496, +3989)
0.6765
Ratio of AUC DCI-IPG/AUC insulin (%/µIU/mL)
+1.085 (−0.709, 1.663)
+1.049 (−0.798, 1.380)
0.8805
Data are expressed as mean (95% confidence interval). for within group difference between baseline and after weight loss. for within group difference between baseline and after weight loss. for within group difference between baseline and after weight loss.
