Predictive Factors of Development of Graves’ Ophthalmopathy for Patients with Juvenile Graves’ Disease

Table 4

Risk factors for GO development in juvenile GD patients: univariate logistic regression.

Factor	Value	β	OR	95% CI
Gender	Female		1.000
	Male	1.181	3.259	1.150	9.235	0.026
Smoking	No		1.000
	Yes	2.061	7.857	2.285	27.017	0.001
Family history of thyroid disease	No		1.000
	Yes	1.261	3.529	1.581	7.878	0.002
Drug-induced hypothyroidism	No		1.000
	Yes	0.863	2.371	0.793	7.086	0.122
Stress before GD	No		1.000
	Yes	1.377	3.963	1.651	9.516	0.002
FT4, pmol/L	0–35.99		1.000
	36.00+	1.764	5.833	2.407	14.137	<0.001
FT3, pmol/L	0–11.99		1.000
	12.00+	1.535	4.643	1.901	11.338	0.001
TSH, mU/L	0.020+		1.000
	0–0.019	0.520	1.683	0.765	3.700	0.195
AntiTPO, kU/L	0–79		1.000
	80+	0.526	1.692	0.773	3.706	0.188
TRAb, U/L	0–15.99		1.000
	16.00+	2.303	10.000	3.487	28.679	<0.001
AntiTG, kU/L	0–79		1.000
	80+		0.778	0.230	2.628	0.686
Age at the diagnosis, years	0–17		1.000
	18+	0.087	1.091	0.512	2.324	0.822

β: regression coefficient; OR: odds ratio; CI: confidence interval.