Long-Term Clinical Outcomes of Invasive Giant Prolactinomas after a Mean Ten-Year Followup

Table 2

Pretreatment manifestations in 25 patients with IGPs.

Pretreatment presentations	Patient number	% of patients
Visual change	13	52
Headache	10	40
Dizziness	1	4
Hypopituitarism	2	8
Cognitive decline	1	4
Decreased sexual function^†	13	72
Amenorrhea^‡	5	71
Galactorrhea^‡	2	29
Nasal obstruction and hemorrhage	2	8
Axillary and pubic hair loss	5	28

In males, the decreased sexual function was 13/18.
^‡In females, the incidence of amenorrhea and galactorrhea was 5/7 and 2/7, respectively.