Therapeutic Outcome of Second Primary Malignancies in Patients with Well-Differentiated Thyroid Cancer
Table 2
Multivariate analysis by Cox proportional hazards regression model for survival and total mortality in 2,864 patients with well-differentiated thyroid cancer.
β coefficient
Hazard ratio
95% confidence interval
value
Lower bound
Upper bound
Age (year)
0.071
1.074
1.0598
1.0880
0.0000
Gender (F/M)
0.275
1.317
0.9743
1.7790
0.0733
SPM (without/with SPM)
0.860
2.363
1.6987
3.2861
0.0000
Postop 131I accumulative dose (mCi)
0.000
0.999
0.9995
1.0004
0.7388
Radio therapy (no/yes)
1.289
3.628
2.5705
5.1209
0.0000
TNM stage (SI/SII/SIII/SIV)
0.260
1.305
1.1317
1.5056
0.0003
Postop 1-month Tg (ng/mL)
0.000
1.000
1.0000
1.0001
0.0000
Tumor size (cm)
0.0462
1.047
0.9896
1.1082
0.1099
Thyroid operative method (less than total/total thyroidectomy)
