Research Article

Metabolic Syndrome in People Living with Human Immunodeficiency Virus: An Assessment of the Prevalence and the Agreement between Diagnostic Criteria

Table 2

Characteristics of the HIV-infected participants.

CharacteristicsTotalMenWomen value
Median (25th–75th percentiles)

Age (years)38 (32–44)41 (35–47)37 (31–43)<0.001
Anthropometry
Body mass index (kg/m2)26.3 (22.1–32)21.4 (19.8–22.4)28.3 (23.8–28.9)<0.001
Waist circumference (cm)88 (78–98)79 (74–88)90 (80–101)<0.001
Waist-to-hip ratio0.86 (0.8–0.91)0.87 (0.84–0.93)0.85 (0.8–0.9)<0.001

Blood pressure (mmHg)
Systolic117 (107–130)123.5 (114.5–140)115 (105.8–127)<0.001
Diastolic82 (75–91)83 (76–94)81.5 (74.8–89.8)0.129

Lipid variables (mmol/L)
Total cholesterol4.3 (3.7–5.1)4.2 (3.5–3.8)4.4 (3.8–5.1)0.009
LDL-C2.5 (2.0–3.1)2.3 (1.7–3.0)2.5 (2.0–3.1)0.012
HDL-C1.3 (1–1.5)1.2 (1.0–1.5)1.29 (1.08–1.52)0.010
Triglycerides1 (0.7–1.3)1.12 (0.75–1.27)0.97 (0.74–1.28)0.023
Fasting glucose (mmol/L)5 (4.6–5.4)5.1 (4.8–5.5)4.9 (4.6–5.4)0.010
HOMA-IR1.36 (0.84–2.24)0.94 (0.53–1.64)1.49 (0.93–2.37)<0.001

HIV-related factors
HIV duration (years)5 (2–9)4 (2–7)5 (2.5–9)<0.001
CD4 count (cells/mm3)392 (240–604)272 (193–448)410 (253–627)0.001

Number (%)
Antiretroviral treatment0.005
None46 (6.6)7 (4.7)39 (7.1)
1st line426 (60.9)78 (52.3)348 (63.3)
2nd line79 (11.3)17 (11.4)62 (11.3)
Others148 (21.2)47 (31.5)101 (18.3)

LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; HIV: human immunodeficiency virus; HOMA index: homeostatic model assessment of insulin resistance.