Table of Contents Author Guidelines Submit a Manuscript
International Journal of Endocrinology
Volume 2017 (2017), Article ID 1617458, 8 pages
https://doi.org/10.1155/2017/1617458
Research Article

Correlation between Insulin Resistance and Thyroid Nodule in Type 2 Diabetes Mellitus

1Key Laboratory of Hormones and Development (Ministry of Health), Tianjin Key Laboratory of Metabolic Diseases, Tianjin Metabolic Diseases Hospital & Tianjin Institute of Endocrinology, Tianjin Medical University, Tianjin, China
2Tianjin University of Traditional Chinese Medicine, Tianjin, China

Correspondence should be addressed to Changlin Ni

Received 15 April 2017; Accepted 31 July 2017; Published 12 October 2017

Academic Editor: Thomas J. Fahey

Copyright © 2017 Yunzhao Tang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. R. H. Eckel, S. M. Grundy, and P. Z. Zimmet, “The metabolic syndrome,” Lancet, vol. 365, pp. 1415–1428, 2005. View at Publisher · View at Google Scholar · View at Scopus
  2. G. Reaven, “The metabolic syndrome or the insulin resistance syndrome? Different names, different concepts, and different goals,” Endocrinology and Metabolism Clinics of North America, vol. 33, no. 2, pp. 283–303, 2004. View at Publisher · View at Google Scholar · View at Scopus
  3. D. L. Roith and Y. Zick, “Recent advances in our understanding of insulin action and insulin resistance,” Diabetes Care, vol. 24, pp. 588–597, 2001. View at Publisher · View at Google Scholar
  4. Z. Heidari, M. A. Mashhadi, and S. Nosratzehi, “Insulin resistance in patients with benign thyroid nodules,” Archives of Iranian Medicine, vol. 18, no. 9, pp. 572–576, 2015. View at Google Scholar
  5. S. Ayturk, A. Gursoy, A. Kut, C. Anil, A. Nar, and N. B. Tutuncu, “Metabolic syndrome and its components are associated with increased thyroid volume and nodule prevalence in a mild-to-moderate iodine-deficient area,” European Journal of Endocrinology, vol. 161, no. 4, pp. 599–605, 2009. View at Publisher · View at Google Scholar · View at Scopus
  6. J. Rezzonico, M. Rezzonico, E. Pusiol, F. Pitoia, and H. Niepomniszcze, “Introducing the thyroid gland as another victim of the insulin resistance syndrome,” Thyroid, vol. 18, pp. 461–464, 2008. View at Publisher · View at Google Scholar · View at Scopus
  7. C. Anil, A. Akkurt, S. Ayturk, A. Kut, and A. Gursoy, “Impaired glucose metabolism is a risk factor for increased thyroid volume and nodule prevalence in a mild-to-moderate iodine deficient area,” Metabolism, vol. 62, pp. 970–975, 2013. View at Publisher · View at Google Scholar · View at Scopus
  8. H. Gharib and E. Papini, “Thyroid nodules: clinical importance, assessment, and treatment,” Endocrinology and Metabolism Clinics of North America, vol. 36, pp. 707–735, 2007. View at Publisher · View at Google Scholar · View at Scopus
  9. L. Hegedüs, “The Thyroid Nodule,” New England Journal of Medicine, vol. 351, no. 17, pp. 1764–1771, 2004. View at Publisher · View at Google Scholar · View at Scopus
  10. Society, C. D, “China guideline for type 2 diabetes (2013),” Chinese Journal of Diabetes Mellitus, vol. 7, pp. 447–498, 2014. View at Google Scholar
  11. N. Knudsen, I. Bulow, P. Laurberg, L. Ovesen, H. Perrild, and T. Jørgensen, “Parity is associated with increased thyroid volumes solely among smokers in an area with moderate to mild iodine deficiency,” European Journal of Endocrinology, vol. 146, pp. 39–43, 2002. View at Publisher · View at Google Scholar
  12. R. Rossi, M. C. Zatelli, P. Franceschetti et al., “Inhibitory effect of dihydrotestosterone on human thyroid cell growth,” The Journal of Endocrinology, vol. 151, no. 2, pp. 185–194, 1996. View at Publisher · View at Google Scholar
  13. E. Bonora, G. Targher, M. Alberiche et al., “Homeostasis model assessment closely mirrors the glucose clamp technique in the assessment of insulin sensitivity: studies in subjects with various degrees of glucose tolerance and insulin sensitivity,” Diabetes Care, vol. 23, no. 1, pp. 57–63, 2002. View at Publisher · View at Google Scholar
  14. H. Y. Yasar, Ö. Ertuğrul, B. Ertuğrul, D. Ertuğrul, and M. Şahin, “Insulin resistance in nodular thyroid disease,” Endocrine Research, vol. 36, no. 4, pp. 167–174, 2011. View at Publisher · View at Google Scholar · View at Scopus
  15. C. Anil, A. Kut, B. Atesagaoglu, A. Nar, N. Bascil Tutuncu, and A. Gursoy, “Metformin decreases thyroid volume and nodule size in subjects with insulin resistance: a preliminary study,” Medical Principle and Practice, vol. 25, no. 3, pp. 233–236, 2016. View at Publisher · View at Google Scholar · View at Scopus
  16. American Diabetes Association, “Diagnosis and classification of diabetes mellitus,” Diabetes Care, vol. 1, Supplement 1, pp. S55–S60, 2008. View at Publisher · View at Google Scholar · View at Scopus
  17. I. Mitchell, E. H. Livingston, A. Y. Chang et al., “Trends in thyroid cancer demographics and surgical therapy in the United States,” Surgery, vol. 142, no. 6, pp. 823–828, 2007. View at Publisher · View at Google Scholar · View at Scopus
  18. American Diabetes Association, “Consensus development conference on insulin resistance,” Diabetes Care, vol. 21, pp. 310–314, 1998. View at Publisher · View at Google Scholar
  19. R. Junik, M. Kozinski, and K. Debska-Kozinska, “Thyroid ultrasound in diabetic patients without overt thyroid disease,” Acta Radiologica, vol. 47, no. 7, pp. 687–691, 2006. View at Publisher · View at Google Scholar · View at Scopus
  20. N. Knudsen, P. Laurberg, H. Perrild, I. Bülow, L. Ovesen, and T. Jørgensen, “Risk factors for goiter and thyroid nodules,” Thyroid, vol. 12, no. 10, pp. 879–888, 2002. View at Publisher · View at Google Scholar
  21. R. K. Orosco, T. Hussain, K. T. Brumund, D. K. Oh, D. C. Chang, and M. Bouvet, “Analysis of age and disease status as predictors of thyroid cancer-specific mortality using the surveillance, epidemiology, and end results database,” Thyroid, vol. 25, pp. 125–132, 2015. View at Publisher · View at Google Scholar · View at Scopus
  22. V. Vella, L. Sciacca, G. Pandini et al., “The IGF system in thyroid cancer: new concepts,” Molecular Pathology, vol. 54, pp. 121–124, 2001. View at Publisher · View at Google Scholar · View at Scopus
  23. B. F. van der Laan, J. L. Freeman, and S. L. Asa, “Expression of growth factors and growth factor receptors in normal and tumorous human thyroid tissues,” Thyroid, vol. 5, no. 1, pp. 67–73, 1995. View at Publisher · View at Google Scholar
  24. E. Blanc, C. Ponce, D. Brodschi et al., “Association between worse metabolic control and increased thyroid volume and nodular disease in elderly adults with metabolic syndrome,” Metabolic Syndrome and Related Disorders, vol. 13, no. 5, pp. 221–226, 2015. View at Publisher · View at Google Scholar · View at Scopus
  25. K. Pazaitou-Panayiotou, G. Panagiotou, S. A. Polyzos, and C. S. Mantzoros, “Serum adiponectin and insulin-like growth factor 1 in predominantly female patients with thyroid cancer: association with the histologic characteristics of the tumor,” Endocrine Practice, vol. 22, no. 1, pp. 68–75, 2015. View at Publisher · View at Google Scholar · View at Scopus
  26. F. Pitoia, E. Abelleira, F. Bueno, C. Urciuoli, A. Schmidt, and H. Niepomniszcze, “Insulin resistance is another factor that increases the risk of recurrence in patients with thyroid cancer,” Endocrine, vol. 48, no. 3, pp. 894–901, 2015. View at Publisher · View at Google Scholar · View at Scopus
  27. M. I. Schmidt, B. B. Duncan, A. Vigo et al., “Leptin and incident type 2 diabetes: risk or protection?” Diabetologia, vol. 49, pp. 2086–2096, 2006. View at Publisher · View at Google Scholar · View at Scopus
  28. M. Rosenbaum, J. Hirsch, E. Murphy, and R. L. Leibel, “Effects of changes in body weight on carbohydrate metabolism, catecholamine excretion, and thyroid function,” The American Journal of Clinical Nutrition, vol. 71, no. 6, pp. 1421–1432, 2000. View at Google Scholar
  29. H. Tahirović, V. Dućić, and A. Smajić, “Euthyroid sick syndrome in type I diabetes mellitus in children and adolescents,” Acta Paediatrica Hungarica, vol. 31, no. 1, pp. 67–73, 1991. View at Google Scholar
  30. P. Singh, S. Khan, and R. K. Mittal, “Assessment of thyroid disfuntion in the type 2 of diabetis patient,” International Journal of Diabetes in Developing Countries, vol. 34, no. 4, p. 229, 2014. View at Publisher · View at Google Scholar · View at Scopus
  31. A. M. Neto, M. C. R. Parisi, M. A. Tambascia, E. J. Pavin, S. M. Alegre, and D. E. Zantut-Wittmann, “Relationship of thyroid hormone levels and cardiovascular events in patients with type 2 diabetes,” Endocrine, vol. 45, no. 1, pp. 84–91, 2014. View at Publisher · View at Google Scholar · View at Scopus
  32. J. C. Pickup, G. D. Chusney, S. M. Thomas, and D. Burt, “Plasma interleukin-6, tumour necrosis factor α and blood cytokine production in type 2 diabetes,” Life Sciences, vol. 67, no. 3, pp. 291–300, 2000. View at Publisher · View at Google Scholar · View at Scopus
  33. T. van der Poll, J. A. Romijn, W. M. Wiersinga, and H. P. Sauerwein, “Tumor necrosis factor: a putative mediator of the sick euthyroid syndrome in man,” The Journal of Clinical Endocrinology and Metabolism, vol. 71, no. 6, pp. 1567–1572, 1990. View at Publisher · View at Google Scholar · View at Scopus
  34. L. B. Leiria, J. M. Dora, S. M. Wajner, A. A. F. Estivalet, D. Crispim, and A. L. Maia, “The rs225017 polymorphism in the 3 UTR of the human DIO2 gene is associated with increased insulin resistance,” PLoS One, vol. 9, no. 8, article e103960, 2014. View at Publisher · View at Google Scholar · View at Scopus
  35. G. Roef, B. Lapauw, S. Goemaere et al., “Body composition and metabolic parameters are associated with variation in thyroid hormone levels among euthyroid young men,” European Journal of Endocrinology, vol. 167, no. 5, pp. 719–726, 2012. View at Publisher · View at Google Scholar · View at Scopus
  36. G. Moriggi, C. V. Verga Falzacappa, C. Mangialardo et al., “Thyroid hormones (T3 and T4): dual effect on human cancer cell proliferation,” Anticancer Research, vol. 31, no. 1, pp. 89–96, 2011. View at Google Scholar
  37. G. Rosano, C. Vitale, A. Silvestri, and M. Fini, “The metabolic syndrome in women: implications for therapy,” International Journal of Clinical Practice Supplement, vol. 3, no. 139, pp. 20–25, 2004. View at Google Scholar
  38. W. Tu, G. Zhang, S. Yu, J. Tang, and J. Yu, “Observations on factors that influence thyroid nodules in diabetic and non-diabetic patients in the Zhejiang province of China,” International Journal of Clinical and Experimental Medicine, vol. 8, no. 10, pp. 19332–19338, 2015. View at Google Scholar
  39. C. Han, X. He, X. Xia et al., “Subclinical hypothyroidism and type 2 diabetes: a systematic review and meta-analysis,” PLoS One, vol. 10, no. 8, article e0135233, 2015. View at Publisher · View at Google Scholar · View at Scopus
  40. C. Wang, “The relationship between type 2 diabetes mellitus and related thyroid diseases,” Journal of Diabetes Research, vol. 2013, Article ID 390534, 9 pages, 2013. View at Publisher · View at Google Scholar · View at Scopus
  41. G. Derosa, P. Maffioli, A. D'Angelo, E. Fogari, L. Bianchi, and A. F. Cicero, “Acarbose on insulin resistance after an oral fat load: a double-blind, placebo controlled study,” Journal of Diabetes and its Complications, vol. 25, no. 4, pp. 258–266, 2011. View at Publisher · View at Google Scholar · View at Scopus
  42. T. Yan, Y. Tang, G. Wang et al., “Relationship between insulin resistance and thyroid nodules in type 2 diabetes in iodine-sufficient areas,” Diabetes/Metabolism Research and Reviews, vol. 32, Supplement 2, pp. 19-20, 2016. View at Google Scholar