Review Article

The Biphasic Effect of Vitamin D on the Musculoskeletal and Cardiovascular System

Table 1

Daily vitamin D recommendations and daily upper tolerable intake levels by different organizations [6, 1012].

Life Stage GroupRecommendationsUpper tolerable intake level
D-A-CH1,2IOM3ES4,5EFSA6IOMES

Infants
 0–6 months400400400–1000100010002000
 6 to 12 months400400400–1000100015002000
Children
 1–3 yr800600600–1000200025004000
 4–8 yr800600600–1000200030004000
Males
 9–13 yr800600600–10002000–400040004000
 14–18 yr800600600–1000400040004000
 19–30 yr8006001500–20004000400010,000
 31–50 yr8006001500–20004000400010,000
 51–70 yr8006001500–20004000400010,000
 70+ yr8008001500–20004000400010,000
Females
 9.13 yr800600600–1000400040004000
 14–18 yr800600600–1000400040004000
 19–30 yr8006001500–20004000400010,000
 31–50 yr8006001500–20004000400010,000
 51–70 yr8006001500–20004000400010,000
 70+ yr8008001500–20004000400010,000
Pregnancy
 14–18 yr800600600–1000400040004000
 19–30 yr8006001500–20004000400010,000
 31–50 yr8006001500–20004000400010,000
Lactation
 14–18 yr800600600–1000400040004000
 19–30 yr8006001500–20004000400010,000
 31–50 yr8006001500–20004000400010,000

1German, Austrian, Swiss Nutrition Societies. 2In the absence of skin synthesis of vitamin D. 3Institute of Medicine. 4Endocrine Society. 5For patients at risk for 25-hydroxyvitamin D levels < 50 nmol/L. 6European Food Safety Authority. Vitamin D data are presented as international units.