Table 2: Blood pressure and RAAS activity before and after lisinopril intervention.

PreinterventionPostinterventionDelta value

With P-HPT,
SBP, mmHg123.7 (15.7)117.3 (14.7)−6.40.006
DBP, mmHg74.5 (8.7)70.1 (7.7)−4.40.003
MAP, mmHg92.7 (12.4)86.8 (11.1)−5.90.002
Supine serum aldosterone, ng/dL4.6 (3.0)4.3 (3.2)−0.30.50
PRA, ng/mL·hr0.5 (0.4)1.9 (2.7)+1.50.06
Aldosterone-to-renin ratio26.3 (39.0)26.2 (40.5)−0.150.98
24 h urinary aldosterone excretion rate, ng/dL·μg/TV11.7 (18.3)7.8 (8.9)−3.90.22
24 h urinary sodium excretion, mmol/day239.8 (59.1)239.6 (94.1)−0.20.99
Without P-HPT,
SBP, mmHg117.4 (15.1)108.2 (12.2)−9.2<0.0001
DBP, mmHg72.1 (11.2)66.3 (9.3)−5.80.0002
MAP, mmHg87.7 (12.6)79.9 (9.7)−7.80.003
Supine serum aldosterone, ng/dL3.4 (1.6)4.7 (5.0)+1.30.26
PRA, ng/mL·hr0.5 (0.4)4.4 (6.1)+3.90.02
Aldosterone-to-renin ratio13.6 (11.7)4.2 (5.5)−9.40.0002
24 h urinary aldosterone excretion rate, ng/dL·μg/TV5.7 (3.5)6.1 (9.1)+0.40.86
24 h urinary sodium excretion, mmol/day231.9 (82.2)203.4 (74.9)−28.50.21

Values are mean (SD) unless otherwise noted. values are paired t-tests. RAAS: renin-angiotensin-aldosterone system; HPT: hyperparathyroidism; SBP: systolic blood pressure; DBP: diastolic blood pressure; MAP: mean arterial pressure; PRA: plasma renin activity.