Research Article

Serum-Free Thyroxine Levels Were Associated with Pulmonary Hypertension and Pulmonary Artery Systolic Pressure in Euthyroid Patients with Coronary Artery Disease

Table 5

Multiple linear regression analysis for pulmonary artery systolic pressure.

Independent
variables
Model 1
β ± SE
Model 2
β ± SE
Model 3
β ± SE

Gender−0.32 ± 0.67−0.58 ± 0.65−0.49 ± 0.65
Age0.10 ± 0.030.11 ± 0.030.11 ± 0.03
BMI0.03 ± 0.090.05 ± 0.090.03 ± 0.09
SBP−0.02 ± 0.02−0.02 ± 0.02−0.02 ± 0.02
Smoking1.45 ± 1.001.39 ± 0.991.42 ± 1.00
Hypertension0.34 ± 0.670.32 ± 0.670.38 ± 0.67
ACEI & ARB0.08 ± 0.570.07 ± 0.570.08 ± 0.57
CCB−0.45 ± 0.67−0.49 ± 0.67−0.43 ± 0.67
Nitrates−0.30 ± 0.55−0.31 ± 0.55−0.27 ± 0.55
LVEF−0.14 ± 0.03−0.13 ± 0.03−0.14 ± 0.03
FT3−0.53 ± 0.49//
FT4/0.27 ± 0.12/
TSH//0.00 ± 0.15

PASP: pulmonary artery systolic pressure; BMI: body mass index; SBP: systolic blood pressure; FT4: free thyroxine; FT3: free triiodothyronine; TSH: thyroid-stimulating hormone; LVEF: left ventricular ejection fraction; CCB: calcium channel blockers; ACEI & ARB: ACE inhibitors and angiotensin II receptor antagonists. Independent variables included in the original model are as follows: model 1: FT3, gender, age, BMI, smoking, LVEF, SBP, history of hypertension, CCB, ACE & ARB, and nitrates; model 2: FT4, gender, age, BMI, smoking, LVEF, SBP, history of hypertension, CCB, ACE & ARB, and nitrates; and model 3: TSH, gender, age, BMI, smoking, LVEF, SBP, history of hypertension, CCB, ACE & ARB, and nitrates. .