International Journal of Endocrinology / 2017 / Article / Tab 4

Review Article

The Tissue-Selective Estrogen Complex (Bazedoxifene/Conjugated Estrogens) for the Treatment of Menopause

Table 4

Cardiovascular events (venous thromboembolism, stroke, and coronary artery disease) reported in SMART trials (data presented as incidence per 1000 women/year, CI 95%) [53].

DoseVenous thromboembolismStrokeCoronary artery disease

BZA 20 mg/CE 0.45 mg0.3 (0.0–2.0)0.4 (0.0–2.4)2.6 (0.0–5.6)
BZA 20 mg/CE 0.625 mg0 (0.0–1.5)0.2 (0.0–1.9)1.4 (0.0–3.9)
BZA/CE all doses0.7 (0.0–1.5)0.44 (0.0–1.1)2.4 (1.0–3.7)
Placebo0.6 (0.0–2.9)0.0 (0.0–1.7)2.0 (0.0–5.2)

Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.