The Associations of Serum Uric Acid with Obesity-Related Acanthosis nigricans and Related Metabolic Indices

Table 2

Characteristics of participants according to serum UA quartiles in females and males.

Parameters	Quartiles of serum UA in females				for trend
	Q1 (<310)	Q2 (311–360)	Q3 (361–424)	Q4 (≥425)
n	54	53	54	54
Age (years)	33 (19)	29 (12)	28 (11)	26 (12)	0.001
BMI (kg/m^2)	31.54 ± 4.64	31.20 ± 4.06	32.74 ± 4.20	34.58 ± 4.77	<0.001
Waist circumference (cm)	100.96 ± 13.45	101.63 ± 12.04	103.91 ± 10.18	106.84 ± 11.01	<0.001
Hip circumference (cm)	107.89 ± 10.45	109.49 ± 8.62	111.87 ± 9.00	113.68 ± 9.57	<0.001
SBP (mmHg)	129.1 ± 15.9	129.6 ± 18.8	131.3 ± 15.6	133.3 ± 16.9	<0.001
DBP (mmHg)	82.4 ± 9.3	83.5 ± 12.2	86.4 ± 12.5	87.4 ± 10.7	<0.001
TC (mmol/L)	4.84 ± 0.99	4.99 ± 1.25	4.92 ± 0.99	5.13 ± 0.98	0.010
TG (mmol/L)	1.69 ± 1.06	1.43 ± 0.76	1.66 ± 1.02	2.35 ± 2.95	<0.001
HDL (mmol/L)	1.12 ± 0.26	1.15 ± 0.20	1.15 ± 0.28	1.16 ± 0.57	0.001
LDL (mmol/L)	2.99 ± 0.89	3.18 ± 1.05	2.98 ± 0.93	3.03 ± 0.98	0.040
Acanthosis nigricans (%)	25.9	22.6	33.3	66.7	<0.001
Parameters	Quartiles of serum UA in males				for trend
	Q1 (<393)	Q2 (394–458)	Q3 (459–528)	Q4 (≥529)
n	49	49	50	48
Age (years)	28 (13)	30 (13)	27 (12)	23 (15)	0.098
BMI (kg/m^2)	34.39 ± 4.81	35.02 ± 4.22	36.32 ± 4.57	37.12 ± 5.48	<0.001
Waist circumference (cm)	112.48 ± 12.87	113.28 ± 9.58	115.41 ± 9.88	119.19 ± 11.86	<0.001
Hip circumference (cm)	114.26 ± 9.22	113.10 ± 7.04	115.69 ± 8.69	120.46 ± 11.42	<0.001
SBP (mmHg)	135.4 ± 14.2	135.2 ± 14.5	135.4 ± 14.1	142.1 ± 15.8	0.005
DBP (mmHg)	83.9 ± 10.3	85.0 ± 10.9	85.2 ± 10.7	84.4 ± 12.8	0.912
TC (mmol/L)	4.72 ± 0.83	5.18 ± 1.11	5.06 ± 1.03	4.86 ± 0.87	0.359
TG (mmol/L)	1.67 ± 0.93	1.92 ± 1.03	2.04 ± 1.05	1.95 ± 0.97	0.256
HDL (mmol/L)	1.05 ± 0.19	1.00 ± 0.16	1.02 ± 0.23	0.95 ± 0.19	0.005
LDL (mmol/L)	2.95 ± 0.69	3.37 ± 0.96	3.23 ± 0.89	3.09 ± 0.76	0.186
Acanthosis nigricans (%)	38.8	59.2	50	79.2	<0.001

value by linear regression analysis and chi-square tests for trends in proportions. ; ; .