Research Article
The Association of Thyrotropin and Autoimmune Thyroid Disease in Developing Papillary Thyroid Cancer
Table 1
Clinicohistopathological characteristics according to pathological results of patients enrolled in the study.
| Result | Benign () | PTC () | value |
| Gender, female (%) | 300 (80.2) | 141 (88.7) | 0.018 | Age (years) | 45.33 ± 15.1 | 47.11 ± 12.8 | 0.194 | BMI (kg/m2) | 23.7 ± 3.7 | 24.2 ± 4.2 | 0.241 | TSH (mIU/L) | 1.6 ± 5.2 | 1.9 ± 1.4 | 0.702 | FT4 (ng/dl) | 1.8 ± 1.4 | 1.3 ± 0.7 | 0.003 | T4 (μg/dl) | 9.0 ± 8.8 | 7.8 ± 2.1 | 0.431 | T3 (ng/dl) | 144.0 ± 82.5 | 111.4 ± 29.6 | 0.007 | Anti-TPO Ab positive (%) | 66 (38.2) | 27 (29.7) | 0.172 | Anti-Tg Ab positive (%) | 10 (16.4) | 14 (20.0) | 0.598 | TRAb positive (%) | 84 (73.7) | 9 (29.0) | 0.000 | MicroPTC (%) | | 34 (21.4) | | Stage | 1 | 115 (72.3) | | | 2 | 11 (6.9) | | | 3 | 12 (7.5) | | | 4 | 21 (13.2) | | LN metastasis (%) | | 47 (29.6) | | Synchronous nonthyroidal malignancies or tumors (%) | | 20 (12.6) | |
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PTC: papillary thyroid cancer; BMI: body mass index; TSH: thyroid-stimulating hormone; FT4: free thyroxine; T4: thyroxine; T3: triiodothyronine; anti-TPO Ab: thyroid peroxidase antibodies; anti-TG Ab: antithyroglobulin antibody; TRAb: TSH receptor antibody; HT: Hashimoto’s thyroiditis; microPTC: papillary thyroid microcarcinoma; LN: lymph node.
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