Research Article

The Association of Thyrotropin and Autoimmune Thyroid Disease in Developing Papillary Thyroid Cancer

Table 1

Clinicohistopathological characteristics according to pathological results of patients enrolled in the study.

ResultBenign ()PTC () value

Gender, female (%)300 (80.2)141 (88.7)0.018
Age (years)45.33 ± 15.147.11 ± 12.80.194
BMI (kg/m2)23.7 ± 3.724.2 ± 4.20.241
TSH (mIU/L)1.6 ± 5.21.9 ± 1.40.702
FT4 (ng/dl)1.8 ± 1.41.3 ± 0.70.003
T4 (μg/dl)9.0 ± 8.87.8 ± 2.10.431
T3 (ng/dl)144.0 ± 82.5111.4 ± 29.60.007
Anti-TPO Ab positive (%)66 (38.2)27 (29.7)0.172
Anti-Tg Ab positive (%)10 (16.4)14 (20.0)0.598
TRAb positive (%)84 (73.7)9 (29.0)0.000
MicroPTC (%)34 (21.4)
Stage1115 (72.3)
211 (6.9)
312 (7.5)
421 (13.2)
LN metastasis (%)47 (29.6)
Synchronous nonthyroidal malignancies or tumors (%)20 (12.6)

PTC: papillary thyroid cancer; BMI: body mass index; TSH: thyroid-stimulating hormone; FT4: free thyroxine; T4: thyroxine; T3: triiodothyronine; anti-TPO Ab: thyroid peroxidase antibodies; anti-TG Ab: antithyroglobulin antibody; TRAb: TSH receptor antibody; HT: Hashimoto’s thyroiditis; microPTC: papillary thyroid microcarcinoma; LN: lymph node.