Research Article
The Association of Thyrotropin and Autoimmune Thyroid Disease in Developing Papillary Thyroid Cancer
Table 4
Univariate analysis: related variables in patients with papillary thyroid cancer excluding those with Graves’ disease who received thyroidectomy.
| Result | Benign () | PTC () | value |
| Gender, female (%) | 221 (84.0) | 126 (87.5) | 0.346 | Age (years) | 49.2 ± 14.5 | 47.2 ± 12.9 | 0.165 | BMI (kg/m2) | 23.9 ± 3.6 | 24.1 ± 4.1 | 0.638 | TSH (mIU/L) | 1.9 ± 5.15 | 1.9 ± 1.4 | 0.975 | TSH with group | | | 0.003 | (i) Group 1 (<0.14) | 19 (10.6) | 3 (2.5) | (ii) Group 2 (0.14–1.04) | 64 (35.8) | 29 (24.2) | (iii) Group 3 (1.04–1.92) | 48 (26.8) | 46 (38.3) | (iv) Group 4 (>1.92) | 48 (26.8) | 42 (35.0) | FT4 (ng/dl) | 1.3 ± 0.52 | 1.2 ± 0.2 | 0.130 | T4 (μg/dl) | 8.9 ± 10.6 | 7.4 ± 1.2 | 0.445 | T3 (ng/dl) | 106.9 ± 40.7 | 106.5 ± 21.9 | 0.955 | Anti-TPO Ab positive (%) | 18 (15.9) | 22 (26.8) | 0.063 | Anti-Tg Ab positive (%) | 4 (8.9) | 11 (17.2) | 0.219 | TRAb positive (%) | 7 (24.1) | 2 (9.5) | 0.192 | MicroPTC (%) | | 26 (18.1) | | Stage | 1 | 101 (70.1) | | 2 | 11 (7.6) | | 3 | 11 (7.6) | | 4 | 21 (14.6) | | LN metastasis (%) | | 46 (31.9) | | Synchronous nonthyroidal malignancies or tumors (%) | | 19 (13.2) | |
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PTC: papillary thyroid cancer; BMI: body mass index; TSH: thyroid-stimulating hormone; FT4: free thyroxine; T4: thyroxine; T3: triiodothyronine; anti-TPO Ab: thyroid peroxidase antibodies; anti-TG Ab: antithyroglobulin antibody; TRAb: TSH receptor antibody; HT: Hashimoto’s thyroiditis; microPTC: papillary thyroid microcarcinoma; LN: lymph node.
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