Research Article
The Association of Thyrotropin and Autoimmune Thyroid Disease in Developing Papillary Thyroid Cancer
Table 5
Subgroup analysis of patients with coexisting Hashimoto’s thyroiditis.
| | Result | Benign () | PTC (N = 38) | value |
| | Gender, female (%) | 56 (80.0) | 36 (94.7) | 0.040 | | Age (years) | 40.3 ± 16.0 | 44.2 ± 10.5 | 0.181 | | BMI (kg/m2) | 23.8 ± 4.1 | 23.7 ± 4.4 | 0.917 | | TSH (mIU/L) | 1.9 ± 8.3 | 1.8 ± 1.7 | 0.923 | | TSH with group | | | 0.000 | | (i) Group 1 (<0.14) | 41 (60.3) | 3 (8.8) | | (ii) Group 2 (0.14–1.04) | 10 (14.7) | 6 (17.6) | | (iii) Group 3 (1.04–1.92) | 5 (7.4) | 13 (38.2) | | (iv) Group 4 (>1.92) | 12 (17.6) | 12 (35.3) | | FT4 (ng/dl) | 2.4 ± 1.95 | 1.3 ± 0.5 | 0.006 | | T4 (μg/dl) | 9.2 ± 4.2 | 7.97 ± 1.3 | 0.362 | | T3 (ng/dl) | 190.8 ± 102.2 | 125.9 ± 34.2 | 0.024 | | TRAb positive (%) | 41 (82.0) | 3 (27.3) | 0.000 | | MicroPTC (%) | | 10 (26.3) | | | Stage | 1 | 31 (81.6) | | | 2 | 2 (5.3) | | | 3 | 2 (5.3) | | | 4 | 3 (7.9) | | | LN metastasis (%) | | 13 (34.2) | | | Synchronous nonthyroidal malignancies or tumors (%) | | 6 (15.8) | |
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PTC: papillary thyroid cancer; BMI: body mass index; TSH: thyroid-stimulating hormone; FT4: free thyroxine; T4: thyroxine; T3: triiodothyronine; anti-TPO Ab: thyroid peroxidase antibodies; anti-TG Ab: antithyroglobulin antibody; TRAb: TSH receptor antibody; HT: Hashimoto’s thyroiditis; microPTC: papillary thyroid microcarcinoma; LN: lymph node.
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