Research Article
The Association of Thyrotropin and Autoimmune Thyroid Disease in Developing Papillary Thyroid Cancer
Table 6
Subgroup analysis of patients with positive TSH receptor antibody.
| | Result | Benign (N = 84) | PTC (N = 9) | value |
| | Gender, female (%) | 59 (70.2) | 9 (100) | 0.057 | | Age (years) | 36.7 ± 12.5 | 48.9 ± 9.6 | 0.006 | | BMI (kg/m2) | 23.6 ± 4.3 | 24.0 ± 5.5 | 0.793 | | TSH (mIU/L) | 0.9 ± 4.9 | 1.1 ± 1.3 | 0.915 | | TSH with group | | | 0.018 | | (i) Group 1 (<0.14) | 67 (81.7) | 3 (37.5) | | (ii) Group 2 (0.14–1.04) | 4 (4.9) | 1 (12.5) | | (iii) Group 3 (1.04–1.92) | 3 (3.7) | 2 (25) | | (iv) Group 4 (>1.92) | 8 (9.8) | 2 (25) | | FT4 (ng/dl) | 2.7 ± 2.1 | 1.7 ± 1.2 | 0.206 | | T4 (μg/dl) | 9.7 ± 5.0 | 10.7 ± 4.9 | 0.707 | | T3 (ng/dl) | 194.9 ± 96.4 | 167.5 ± 50.6 | 0.578 | | Anti-TPO Ab positive (%) | 41 (77.4) | 3 (42.9) | 0.052 | | Anti-Tg Ab positive (%) | 6 (46.2) | 1 (33.3) | 0.687 | | MicroPTC (%) | | 5 (55.6) | | | Stage | 1 | 9 (100) | | | 2 | 0 (0) | | | 3 | 0 (0) | | | 4 | 0 (0) | | | LN metastasis (%) | | 1 (11.1) | | | Synchronous nonthyroidal malignancies or tumors (%) | | 1 (11.1) | |
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PTC: papillary thyroid cancer; BMI: body mass index; TSH: thyroid-stimulating hormone; FT4: free thyroxine; T4: thyroxine; T3: triiodothyronine; anti-TPO Ab: thyroid peroxidase antibodies; anti-TG Ab: antithyroglobulin antibody; HT: Hashimoto’s thyroiditis; microPTC: papillary thyroid microcarcinoma; LN: lymph node.
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