Low Levels of Sex Hormone-Binding Globulin Constitute an Independent Risk Factor for Arterial Stiffness in Korean Women

Table 3

Multivariate regression models of sex hormone-binding globulin for brachial-ankle pulse wave velocity.

	Model 1		Model 2		Model 3
	Beta (SE)		Beta (SE)		Beta (SE)
SHBG	−0.098 (0.039)	0.012	−0.087 (0.038)	0.023	−0.082 (0.039)	0.037
Age	0.424 (0.040)	<0.001	0.376 (0.048)	<0.001
Waist circumference	−0.093 (0.040)	0.020	−0.113 (0.039)	0.004
Mean BP	0.424 (0.041)	<0.001	0.397 (0.039)	<0.001
Glucose			0.094 (0.040)	0.020
Ten-year ASCVD risk					0.642 (0.045)	<0.001
FSH			0.030 (0.043)	0.048	0.035 (0.045)	0.414
Adjusted R square	0.516		0.566		0.463

Beta represents standardized regression coefficient. Model 1 includes the variables of SHBG, age, waist circumference, and mean BP; model 2 additionally includes the variables of glucose, FSH, menopause state, hypertension, DM, smoking, drinking, and exercise; model 3 includes the variables of SHBG, ASCVD risk, and FSH; SHBG: sex hormone-binding globulin; BP: blood pressure; ASCVD: atherosclerotic cardiovascular disease; FSH: follicle-stimulating hormone.