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International Journal of Endocrinology
Volume 2017, Article ID 7861236, 14 pages
Research Article

Chronic Hyperinsulinaemic Hypoglycaemia in Rats Is Accompanied by Increased Body Weight, Hyperleptinaemia, and Decreased Neuronal Glucose Transporter Levels in the Brain

1Department of Veterinary Disease Biology, Section for Experimental Animal Models, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
2Department of Toxicology, Safety Pharm and Pathology, Novo Nordisk A/S, Maaloev, Denmark
3Division of Toxicology, Envigo, Eye, Suffolk, UK
4Department of Development DMPK, Novo Nordisk A/S, Maaloev, Denmark
5Department of Development Bioanalysis, Novo Nordisk A/S, Maaloev, Denmark

Correspondence should be addressed to Vivi F. H. Jensen; moc.ksidronovon@jhfv

Received 30 June 2016; Revised 19 December 2016; Accepted 26 December 2016; Published 21 March 2017

Academic Editor: Darío Acuña-Castroviejo

Copyright © 2017 Vivi F. H. Jensen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [2 citations]

The following is the list of published articles that have cited the current article.

  • Vivi F. H. Jensen, Anne-Marie Molck, Henrik Soeborg, Jette Nowak, Melissa Chapman, Jens Lykkesfeldt, and Ingrid B. Bogh, “Proximal Neuropathy and Associated Skeletal Muscle Changes Resembling Denervation Atrophy in Hindlimbs of Chronic Hypoglycaemic Rats,” Basic & Clinical Pharmacology & Toxicology, 2017. View at Publisher · View at Google Scholar
  • Vivi F.H. Jensen, Anne-Marie Mølck, Jens Lykkesfeldt, and Ingrid B. Bøgh, “Effect of maternal hypoglycaemia during gestation on materno-foetal nutrient transfer and embryo-foetal development: Evidence from experimental studies focused primarily on the rat,” Reproductive Toxicology, 2018. View at Publisher · View at Google Scholar