Research Article
Factors Associated with the Prevalence of Thyroid Nodules and Goiter in Middle-Aged Euthyroid Subjects
Table 1
Characteristics of the study population.
| | Characteristic | Men () | Women () | value |
| | Thyroid volume (mL) | 16.5 ± 6.0 | 12.3 ± 5.0 | <0.001 | | Prevalence of goiter, n (%) | 12 (8.5) | 27 (15.4) | 0.06 | Prevalence of thyroid
nodule, n (%) | 28 (19.7) | 71 (40.6) | <0.001 | | Thyroid nodule size (mm) | 12.0 ± 3.3 | 11.2 ± 6.8 | 0.748 | | TSH (mU/L) | 1.2 (0.7) | 1.2 (0.9) | 0.436 | | FT4 (pmol/L) | 15.1 ± 2.1 | 14.5 ± 2.2 | 0.005 | | ATPO (kU/L) | 0.05 (1.1) | 0.3 (1.1) | 0.332 | | Insulin (mU/L) | 9.6 (5.5) | 8.9 (3.5) | 0.042 | | FPG (mmol/L) | 5.2 (0.8) | 4.9 (0.6) | <0.001 | | HOMA-IR | 2.3 (1.4) | 1.9 (1.0) | 0.004 | | Leptin (pg/L) | 4.1 (4.5) | 11.2 (10.7) | <0.001 | | TC (mmol/L) | 6.0 ± 1.1 | 6.0 ± 1.1 | 0.995 | | HDL (mmol/L) | 1.5 (0.5) | 1.8 (0.6) | <0.001 | | LDL (mmol/L) | 3.9 ± 1.0 | 3.6 ± 1.2 | 0.036 | | TG (mmol/L) | 1.3 (0.8) | 1.0 (0.5) | <0.001 | | SBP (mmHg) | 132.7 (23.3) | 126.0 (21.3) | <0.001 | | DBP (mmHg) | 88.7 (13.3) | 80.7 (13.3) | <0.001 | | WC (cm) | 95.8 ± 11.9 | 85.2 ± 13.8 | <0.001 | | BMI (kg/m2) | 26.9 (5.4) | 25.4 (6.7) | 0.076 | | Obesity, n (%) | 34 (23.9) | 36 (20.6) | 0.472 | | Metabolic syndrome, n (%) | 44 (31) | 32 (18.3) | 0.009 | | Smoking, n (%) | 59 (41.5) | 37 (21.1) | <0.001 |
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Mean ± standard deviation; median (interquartile range).
ATPO: antithyroid peroxidase antibodies; BMI: body mass index; DBP: diastolic blood pressure; FPG: fasting plasma glucose; FT4: free thyroxine; HDL: high-density lipoprotein; HOMA-IR: insulin resistance index; LDL: low-density lipoprotein; SBP: systolic blood pressure; TC: total cholesterol; TG: triglycerides; TSH: thyroid stimulating hormone; WC: waist circumference.
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