Review Article

Gender, Estrogen, and Obliterative Lesions in the Lung

Table 1

Summary of PAH registry female to male ratios.

RegistryTimeCohortNumber of patientsFemale : male ratioReferences

REVEAL2006-2007Mean age 53 yr
IPAH, HPAH, APAH, drug-/toxin-induced PAH
25254.1 : 1 IPAH
3.8 : 1 APAH
5.4 : 1 drug-/toxin-induced PAH
[83]
French2002-2003Mean age 50 yr
IPAH, HPAH, drug-/toxin-induced PAH
6741.9 : 1[84]
NIH1981–1985Mean age 36 yr
IPAH, HPAH
1871.7 : 1[85]

IPAH: Idiopathic PAH; HPAH: Heritable PAH; APAH: Associated PAH.