Research Article

Lower Extremity Peripheral Arterial Disease Is an Independent Predictor of Coronary Heart Disease and Stroke Risks in Patients with Type 2 Diabetes Mellitus in China

Table 4

Multivariate binary logistic regression analysis of risk factors for CHD and stroke as estimated using the UKPDS risk engine.

VariablesCHD riskStroke risk
OR (95% CL)OR (95% CL)

years33.2 (20.2–54.4)0.000255.1 (35.5–1832.4.5)0.000
Hypertension2.0 (1.5–2.8)0.0002.1 (1.5–2.8)0.000
Smoking5.5 (3.9–7.6)0.0001.5 (1.1−2.0)0.013
Elevated HbA1c4.5 (3.4–6.1)0.0000.8 (0.6–1.1)0.182
Reduced HDL-c1.4 (1.1–1.9)0.0120.9 (0.7–1.2)0.594
PAD3.6 (2.2–6.0)0.0006.9 (4.0–11.8)0.000

UKPDS: United Kingdom Prospective Diabetes Study; CHD: coronary heart disease. Elevated HbA1c (≥the average value 9.61%); reduced HDL-c (<1.04 mmol/L (men) or <1.29 mmol/L (women)).