Autoimmune Diseases in Patients with Cushing’s Syndrome after Resolution of Hypercortisolism: Case Reports and Literature Review

Table 2

Demographic, anthropometric, hemodynamic, biochemical, and hormonal parameters at baseline and after a 24-month follow-up in patients with treated Cushing’s syndrome (CS) compared with the group of Cushing’s syndrome patients with posttreatment onset of autoimmune diseases (CS with AD).

	Baseline			24-month FU
	CS () A	CS with AD () B		CS () C	CS with AD () D		A vs. C	B vs. D
Age (years)			0.03			0.03	ns	ns
Sex (M/F)	63/37	1/9		63/37	1/9
BMI (kg/m^2)			ns			ns	ns	ns
WC (cm)			ns			ns	ns	0.01
Office SBP (mmHg)			ns			ns	0.01	0.01
Office DBP (mmHg)			ns			ns	0.01	0.02
HR (bpm)			ns			ns	ns	ns
Creatinine (mg/dL)	0.84 ± 0.4	1.05 ± 1.06	ns	0.95 ± 0.35	1.19 ± 1.24	ns	ns	ns
Na^+ (mmol/L)			ns			ns	ns	ns
K^+ (mmol/L)			ns			ns	ns	ns
Calcium (mg/dL)			ns			ns	ns	ns
FG (mg/dL)			ns			ns	ns	ns
Uric acid (mg/dL)			ns			ns	ns	ns
TC (mg/dL)			0.01			ns	ns	0.01
HDL-C (mg/dL)			ns			ns	ns	ns
LDL-C (mg/dL)			0.01			ns	0.03	0.02
TGL (mg/dL)			0.01			ns	ns	ns
UFC (nmol/24 h)			0.001			ns	0.001	0.001
PC (nmol/L)			0.001			ns	0.05	0.001
PC DXM (nmol/L)			0.001			0.001	0.001	0.001

BMI: body mass index; WC: waist circumference; SBP: systolic blood pressure; DBP: diastolic blood pressure; HR: heart rate; Na⁺: serum sodium; K⁺: serum potassium; FG: fasting serum glucose; TC: total cholesterol; HDL-C: HDL cholesterol; LDL-C: LDL cholesterol; TGL: triglycerides; UFC: urinary free cortisol; PC: plasma cortisol; PC DXM: plasma cortisol postovernight 1 mg dexamethasone test.