Research Article

Fasting-Evoked En Route Hypoglycemia in Diabetes (FEEHD): An Overlooked Form of Hypoglycemia in Clinical Practice

Table 1

Characteristics of patients and a summary of survey responses.

Total number of patients invited to enroll in the study, 572
Total number of patients who completed survey, (survey response rate)525 (91.8%)
Final analytic sample, excluding patients with no fasting labs (127) and patients with incomplete data (35)363
Mean age (SD), years60.6 (12.5)
Mean diabetes duration (SD), years16.0 (11.5)
Sex, female194 (53.2%)
Patients reporting type 2 diabetes mellitus, (%)298 (81.6%)
Patients on hypoglycemia-inducing OHAs (without insulin)36
Patients on insulin without hypoglycemia-inducing OHAs215
Patients on both insulin and hypoglycemia-inducing OHAs18
Total at-risk patients for FEEHD269 (74.1%)
Total patients with FEEHD62 (17.1%)
Patients with FEEHD from “at-risk” patient group (prevalence)59 (21.9%)
Multiple FEEHD episode patients7
Patients educated by health care prior to fasting labs131 (35.9%)

FEEHD = fasting-evoked en route hypoglycemia in diabetes; SD = standard deviation; OHA = oral hypoglycemic agent. Sulfonylureas and meglitinide analogues. At-risk patients: patients who had fasting labs done and were on insulin or hypoglycemia-inducing OHAs or both. FEEHD: fasting-evoked en route hypoglycemia in diabetes. 3 patients who had FEEHD were not on any hypoglycemia-inducing OHA or insulin. They were on metformin, saxagliptin, liraglutide, or canagliflozin.