Copy Number Variation of Immune-Related Genes and Their Association with Iodine in Adults with Autoimmune Thyroid Diseases

Table 1

Demographic characteristics of adults in three areas.

Characteristics	Maxi (iodine-adequate group)	Xiwenzhuang (iodine-sufficient group)	Gaoche (iodine-excess group)
N	324	286	291
Sex (N)
Male	132	90	135
Female	192	196	156
Age
Mean ± SD	46 ± 10	52 ± 13	45 ± 12
Range	19–70	18–80	20–66
BMI
Mean ± SD	24.91 ± 3.51	25.30 ± 3.45	25.24 ± 3.61
UIC (μg/L)
P50	126.90	218.60	418.65^#
P25-P75	87.70–209.08	146.80–302.60	277.90–605.85
TgAb-positive rate % (n/N)	13.58 (44/324)	15.73 (45/286)	9.97 (29/291)
TPOAb-positive rate % (n/N)	10.19 (33/324)	11.89 (34/286)	9.28 (27/291)
TgAb- and TPOAb-positive rate % (n/N)	5.86 (19/324)	6.64 (19/286)	5.50 (16/291)
AITD prevalence % (n/N)	17.90 (58/324)	20.98 (60/286)	13.75 (40/291)

BMI: body mass index; UIC: urinary iodine concentration. Compared with the iodine-adequate group, median urinary iodine value was significantly higher in the iodine-sufficient group (, ). ^#Compared with the iodine-adequate group, median urinary iodine value was significantly higher in the iodine-excess group (, ).