High Expression of Somatostatin Receptors 2A, 3, and 5 in Corticotroph Pituitary Adenoma

Table 5

Expression differences between primary and secondary pituitary adenomas.

	Primary PA mean ()	Recurrent PA mean ()	value
Corticotroph
SSTR1	1.46 (62)	3.03 (17)	0.0351
SSTR2A	3.77 (63)	3.54 (17)	0.6985
SSTR3	2.78 (63)	3.43 (16)	0.3674
SSTR4	0.71 (65)	1.67 (16)	0.0174
SSTR5	7.68 (65)	4.95 (17)	0.0370
PIT-1 positive
SSTR1	2.41 (46)	3.25 (8)	0.3047
SSTR2A	6.93 (44)	3.69 (8)	0.0049
SSTR3	0.58 (46)	0.13 (8)	0.0212
SSTR4	1.20 (46)	2.81 (8)	0.0673
SSTR5	5.40 (44)	2.56 (8)	0.0350
Gonadotroph
SSTR1	2.83 (15)	1.86 (7)	0.3551
SSTR2A	1.68 (11)	3.00 (7)	0.2130
SSTR3	2.04 (13)	1.86 (7)	0.8391
SSTR4	1.80 (15)	1.29 (7)	0.3606
SSTR5	0.75 (14)	1.21 (7)	0.3232
Nonfunctioning
SSTR1	3.08 (45)	3.06 (36)	0.9715
SSTR2A	2.40 (42)	3.07 (34)	0.1853
SSTR3	1.61 (42)	1.20 (36)	0.2581
SSTR4	1.53 (43)	1.78 (35)	0.4520
SSTR5	0.79 (43)	1.61 (35)	0.0162