Research Article

Value of Apoptotic, Antiapoptotic, and Cell Proliferation Markers in the Treatment of Graves’ Disease

Table 2

Expression of proliferation (Ki-67) and antiproliferation (p27) cell markers in thyrocytes and lymphocytes according to the diagnosis: Graves’ disease versus normal control (chi-square test/Fisher’s exact test).

Markers%GravesControl value

Ki-67 in thyrocytes<1%56.82%85.71%0.1254
>1%43.18%14.29%
Ki-67 in lymphocytes<1%38.64%71.43%0.0001
>1%61.36%28.57%
p27 in thyrocytes<25%18.18%21.43%0.6892
>25%81.82%78.57%
p27 in lymphocytes<25%63.6492.86%<0.0001
>25%36.36%7.14%