Prevention of Elevation in Plasma Triacylglycerol with High-Dose Bezafibrate Treatment Abolishes Insulin Resistance and Attenuates Glucose Intolerance Induced by Short-Term Treatment with Dexamethasone in Rats

Figure 3

Biochemical data. Fasting plasma (a) triacylglycerol, (b) NEFA, (c) T-Chol, (d) blood glucose, and (e) plasma insulin values. Observe the marked effect of bezafibrate treatment on prevention of elevation of triacylglycerolemia and insulinemia caused by dexamethasone treatment. Fed plasma (f) triacylglycerol, (g) NEFA, (h) T-Chol, (i) blood glucose, and (j) plasma insulin values. We can note the marked effect of bezafibrate treatment on prevention of elevation of plasma triacylglycerol and NEFA and blood glucose. Results are expressed as mean ± SD. Significantly different vs. the respective control group (dexamethasone effect) and ^#significantly different vs. the respective control group (bezafibrate effect) using two-way ANOVA with Tukey’s post hoc test. –12, . NEFA: nonesterified fatty acid; T-Chol: total cholesterol; ns: not significant.