Osteoporosis Is Associated with Deteriorating Clinical Status in Adults with Cystic Fibrosis

Table 7

Multivariate Linear Regression for spine and femoral T and Z score.

Variables	B	SE of B	95% CI of B	β	B	SE of B	95% CI of B	β
Femoral T score					Femoral Z score
Female gender	0.407	0.23	-0.045 - 0.859	0.15	0.349	0.14	-0.075 - 0.775	0.14
BMI	0.056	0.04	-0.012 - 0.125	0.15	0.012	0.03	-0.052 - 0.076	0.04
ppFEV1	0.027	0.01	0.017 - 0.038	0.46	0.022	0.01	0.012 - 0.032	0.42
Chronic Infection	-0.643	0.26	-1.166 to -0.120	-0.18	-0.617	0.25	-1.105 to -0.13	-0.20
Vitamin D	-0.017	0.05	-0.112 - 0.078	0.06	-0.011	0.05	-0.100 - 0.078	-0.02
Estradiol	-0.059	0.42	-0.891 - 0.773	-0.01	-0.110	0.40	-0.883 - 0.669	-0.02
HsCRP log10	-0.292	0.21	-0.705 - 0.12	-0.11	-0.30	-0.13	-0.681 - 0.089	-0.13
Spine T score					Spine Z score
Female gender	0.598	0.23	0.133 – 1.062	0.23	0.560	0.22	0.115 – 1.003	0.24
BMI	0.108	0.04	0.037 – 0.178	0.29	0.027	0.03	-0.047 – 0.094	0.08
ppFEV1	0.015	0.01	0.004 – 0.026	0.26	0.012	0.01	0.002 – 0.023	0.24
Chronic Infection	-0.633	0.27	-1.170 to -0.096	-0.19	-0.724	0.30	-1.237 to –0.211	-0.24
Vitamin D	0.003	0.05	-0.094 – 0.101	0.01	0.000	0.06	-0.093 – 0.094	0.00
Estradiol	0.190	0.43	-0.664 – 1.044	0.04	0.18	0.41	-0.636 – 0.997	0.04
hsCRP log 10	-0.033	0.21	-0.457 – 0.391	-0.01	-0.046	0.20	-0.451 – 0.360	-0.02

. . Vitamin D is square rooted and hsCRP log10 transformed. Model fit: Femoral T score: R² 0.39, adj. R² 0.36, F(7/113)=10.71, . Femoral Z score: R² 0.27, adj. R² 0.32, F(7/113)=7.61, . Spine T score: R² 0.31, adj. R² 0.26, F(7/113)=7.15, . Spine Z score: R² 0.22, adj. R² 0.17, F(7/113)=4.58, .