Vanadyl Sulfate Effects on Systemic Profiles of Metabolic Syndrome in Old Rats with Fructose-Induced Obesity
Vanadyl sulfate (VS) effect on food, liquid, and fructose consumption in old obese male Wistar rats. Obesity was induced in rats with high-fructose diet (HFD) during 28 weeks, using a set of normal diet (ND) rats as comparative groups; stability in food and liquid consumption was observed during 4 weeks. After that, insulin sensitizer treatment (metformin (MET) or VS) was applied from week 32 to week 40, using saline solution (SS) as a control. (a) Weekly food intake after treatment with insulin sensitizers (starting week 32) in both lean (ND) and obese (HFD) rats. comparing VS treatment versus MET and/or SS treatment in lean or obese animals. (b) Weekly water drink consumption after treatment with insulin sensitizers. comparing HFD + VS treatment versus HFD + MET or SS treatment. (c) Weekly fructose consumption after treatment with insulin sensitizers. comparing HFD + VS treatment versus HFD + MET or SS treatment. Data are ().
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