Effects of Estrogen and Estrogen Receptors on Transcriptomes of HepG2 Cells: A Preliminary Study Using RNA Sequencing

<div>Heat map showing and comparing the top gene ontology (GO) biological process (BP) annotation terms among 17<i>β</i>-estradiol (E2), estrogen receptor (ER) <i>α</i> agonist PPT, and ER<i>β</i> agonist DPN treatments of HepG2 cells. Enrichment analysis of differentially expressed genes was performed on the list of (a) upregulated and (b) downregulated genes compared with vehicle-treated HepG2 cells.</div>

International Journal of Endocrinology

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Figure 3: Effects of Estrogen and Estrogen Receptors on Transcriptomes of HepG2 Cells: A Preliminary Study Using RNA Sequencing 