Table of Contents Author Guidelines Submit a Manuscript
International Journal of Endocrinology
Volume 2018, Article ID 6421243, 8 pages
https://doi.org/10.1155/2018/6421243
Clinical Study

Adult Height after Growth Hormone Treatment at Pubertal Onset in Short Adolescents Born Small for Gestational Age: Results from a Belgian Registry-Based Study

1The Belgian Society for Pediatric Endocrinology and Diabetology (BESPEED), Bruxelles, Belgium
2Division of Pediatric Endocrinology, Université catholique de Louvain, CHU UCL Namur, Yvoir, Belgium
3Division of Pediatric Endocrinology, Hôpital Universitaire des Enfants Reine Fabiola (HUDERF), Bruxelles, Belgium
4Division of Pediatric Endocrinology, UZ Antwerpen, Antwerpen, Belgium
5Division of Pediatric Endocrinology, CHU-Notre-Dame des Bruyères, Chênée, Belgium
6Division of Pediatric Endocrinology, Cliniques Universitaires Saint-Luc, Bruxelles, Belgium
7Division of Pediatric Endocrinology, Jessa Ziekenhuis, Hasselt, Belgium
8Division of Pediatric Endocrinology, UZ Leuven, Leuven, Belgium
9Division of Pediatric Endocrinology, UZ Gent, Gent, Belgium
10Department of Public Health and Primary Care, KU Leuven, Leuven, Belgium
11Division of Pediatric Endocrinology, UZ Brussel, Brussel, Belgium

Correspondence should be addressed to J. De Schepper; eb.lessurbzu@reppehcsed.naej

Received 19 October 2017; Revised 17 January 2018; Accepted 6 February 2018; Published 3 April 2018

Academic Editor: Donatella Capalbo

Copyright © 2018 M. Thomas et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. E. M. Bannink, D. J. van, P. G. Mulder, and A. C. Hokken-Koelega, “Free/dissociable insulin-like growth factor (IGF)-I, not total IGF-I, correlates with growth response during growth hormone treatment in children born small for gestational age,” The Journal of Clinical Endocrinology & Metabolism, vol. 92, no. 8, pp. 2992–3000, 2007. View at Publisher · View at Google Scholar · View at Scopus
  2. M. B. Ranke and A. Lindberg, “Height at start, first-year growth response and cause of shortness at birth are major determinants of adult height outcomes of short children born small for gestational age and Silver-Russell syndrome treated with growth hormone: analysis of data from KIGS,” Hormone Research in Paediatrics, vol. 74, no. 4, pp. 259–266, 2010. View at Publisher · View at Google Scholar · View at Scopus
  3. C. P. Houk and P. A. Lee, “Early diagnosis and treatment referral of children born small for gestational age without catch-up growth are critical for optimal growth outcomes,” International Journal of Pediatric Endocrinology, vol. 2012, no. 1, 2012. View at Publisher · View at Google Scholar
  4. P. E. Clayton, S. Cianfarani, P. Czernichow, G. Johannsson, R. Rapaport, and A. Rogol, “Management of the child born small for gestational age through to adulthood: a consensus statement of the International Societies of Pediatric Endocrinology and the Growth Hormone Research Society,” The Journal of Clinical Endocrinology & Metabolism, vol. 92, no. 3, pp. 804–810, 2007. View at Publisher · View at Google Scholar · View at Scopus
  5. A. J. Lem, D. C. van der Kaay, M. A. de Ridder et al., “Adult height in short children born SGA treated with growth hormone and gonadotropin releasing hormone analog: results of a randomized, dose-response GH trial,” The Journal of Clinical Endocrinology & Metabolism, vol. 97, no. 11, pp. 4096–4105, 2012. View at Publisher · View at Google Scholar · View at Scopus
  6. J. M. Tanner and R. H. Whitehouse, “Clinical longitudinal standards for height, weight, height velocity, weight velocity, and stages of puberty,” Archives of Disease in Childhood, vol. 51, no. 3, pp. 170–179, 1976. View at Publisher · View at Google Scholar · View at Scopus
  7. M. Roelants, R. Hauspie, and K. Hoppenbrouwers, “References for growth and pubertal development from birth to 21 years in Flanders, Belgium,” Annals of Human Biology, vol. 36, no. 6, pp. 680–694, 2009. View at Publisher · View at Google Scholar · View at Scopus
  8. A. Niklasson, A. Ericson, J. G. Fryer, J. Karlberg, C. Lawrence, and P. Karlberg, “An update of the Swedish reference standards for weight, length and head circumference at birth for given gestational age (1977-1981),” Acta Paediatrica Scandinavica, vol. 80, no. 8-9, pp. 756–762, 1991. View at Publisher · View at Google Scholar
  9. M. B. Ranke, “Towards a consensus on the definition of idiopathic short stature,” Hormone Research, vol. 45, no. 2, pp. 64–66, 1996. View at Publisher · View at Google Scholar · View at Scopus
  10. D. D. Martin, R. C. Hauspie, and M. B. Ranke, “Total pubertal growth and markers of puberty onset in adolescents with GHD: comparison between mathematical growth analysis and pubertal staging methods,” Hormone Research, vol. 63, no. 2, pp. 95–101, 2005. View at Publisher · View at Google Scholar · View at Scopus
  11. E. Vicens-Calvet, R. M. Espadero, and A. Carrascosa, “Longitudinal study of the pubertal growth spurt in children born small for gestational age without postnatal catch-up growth,” Journal of Pediatric Endocrinology & Metabolism, vol. 15, no. 4, pp. 381–388, 2002. View at Publisher · View at Google Scholar
  12. L. Lazar, U. Pollak, O. Kalter-Leibovici, A. Pertzelan, and M. Phillip, “Pubertal course of persistently short children born small for gestational age (SGA) compared with idiopathic short children born appropriate for gestational age (AGA),” European Journal of Endocrinology, vol. 149, no. 5, pp. 425–432, 2003. View at Publisher · View at Google Scholar · View at Scopus
  13. M. B. Ranke and A. Lindberg, “Prediction models for short children born small for gestational age (SGA) covering the total growth phase. Analyses based on data from KIGS (Pfizer International Growth Database),” BMC Medical Informatics and Decision Making, vol. 11, no. 1, p. 38, 2011. View at Publisher · View at Google Scholar · View at Scopus
  14. J. C. Carel, P. Chatelain, P. Rochiccioli, and J. L. Chaussain, “Improvement in adult height after growth hormone treatment in adolescents with short stature born small for gestational age: results of a randomized controlled study,” The Journal of Clinical Endocrinology & Metabolism, vol. 88, no. 4, pp. 1587–1593, 2003. View at Publisher · View at Google Scholar · View at Scopus
  15. J. Dahlgren and K. A. Wikland, “Final height in short children born small for gestational age treated with growth hormone,” Pediatric Research, vol. 57, no. 2, pp. 216–222, 2005. View at Publisher · View at Google Scholar · View at Scopus
  16. M. A. de Ridder, T. Stijnen, and A. C. Hokken-Koelega, “Prediction model for adult height of small for gestational age children at the start of growth hormone treatment,” The Journal of Clinical Endocrinology & Metabolism, vol. 93, no. 2, pp. 477–483, 2008. View at Publisher · View at Google Scholar · View at Scopus
  17. O. Pinhas-Hamiel, D. Benary, K. Mazor-Aronovich et al., “Advanced bone age and hyperinsulinemia in overweight and obese children,” Endocrine Practice, vol. 20, no. 1, pp. 62–67, 2014. View at Publisher · View at Google Scholar · View at Scopus
  18. J. H. Kwon, H. A. Lee, Y. J. Kim et al., “Effects of adrenal androgen levels on bone age advancement in prepubertal children: using the Ewha birth and growth cohort study,” Journal of Korean Medical Science, vol. 32, no. 6, pp. 968–973, 2017. View at Publisher · View at Google Scholar · View at Scopus
  19. R. Verkauskiene, I. Petraitiene, and W. K. Albertsson, “Puberty in children born small for gestational age,” Hormone Research in Paediatrics, vol. 80, no. 2, pp. 69–77, 2013. View at Publisher · View at Google Scholar · View at Scopus
  20. G. d’Annunzio, M. Vanelli, A. Pistorio et al., “Insulin resistance and secretion indexes in healthy Italian children and adolescents: a multicentre study,” Acta Biomed, vol. 80, no. 1, pp. 21–28, 2009. View at Google Scholar
  21. H. Mellerio, C. Alberti, C. Druet et al., “Novel modeling of reference values of cardiovascular risk factors in children aged 7 to 20 years,” Pediatrics, vol. 129, no. 4, pp. e1020–e1029, 2012. View at Publisher · View at Google Scholar · View at Scopus
  22. E. R. Faria, F. R. Faria, S. C. Franceschini et al., “Insulin resistance and components of metabolic syndrome, analysis by gender and stage of adolescence,” Arquivos Brasileiros de Endocrinologia & Metabologia, vol. 58, no. 6, pp. 610–618, 2014. View at Publisher · View at Google Scholar · View at Scopus
  23. Y. van Pareren, P. Mulder, M. Houdijk, M. Jansen, M. Reeser, and A. Hokken-Koelega, “Adult height after long-term, continuous growth hormone (GH) treatment in short children born small for gestational age: results of a randomized, double-blind, dose-response GH trial,” The Journal of Clinical Endocrinology & Metabolism, vol. 88, no. 8, pp. 3584–3590, 2003. View at Publisher · View at Google Scholar · View at Scopus
  24. V. Boonstra, Y. van Pareren, P. Mulder, and A. Hokken-Koelega, “Puberty in growth hormone-treated children born small for gestational age (SGA),” The Journal of Clinical Endocrinology & Metabolism, vol. 88, no. 12, pp. 5753–5758, 2003. View at Publisher · View at Google Scholar · View at Scopus
  25. F. de Zegher and A. Hokken-Koelega, “Growth hormone therapy for children born small for gestational age: height gain is less dose dependent over the long term than over the short term,” Pediatrics, vol. 115, no. 4, pp. e458–e462, 2005. View at Publisher · View at Google Scholar · View at Scopus
  26. J. C. Carel, E. Ecosse, F. Landier et al., “Long-term mortality after recombinant growth hormone treatment for isolated growth hormone deficiency or childhood short stature: preliminary report of the French SAGhE study,” The Journal of Clinical Endocrinology & Metabolism, vol. 97, no. 2, pp. 416–425, 2012. View at Publisher · View at Google Scholar · View at Scopus
  27. S. A. van Gool, G. A. Kamp, B. H. Visser-van et al., “Final height outcome after three years of growth hormone and gonadotropin-releasing hormone agonist treatment in short adolescents with relatively early puberty,” The Journal of Clinical Endocrinology & Metabolism, vol. 92, no. 4, pp. 1402–1408, 2007. View at Publisher · View at Google Scholar · View at Scopus
  28. J. A. Yanovski, S. R. Rose, G. Municchi et al., “Treatment with a luteinizing hormone–releasing hormone agonist in adolescents with short stature,” The New England Journal of Medicine, vol. 348, no. 10, pp. 908–917, 2003. View at Publisher · View at Google Scholar · View at Scopus