Research Article

Genetic Variability in eIF2α Gene Is Associated with Islet β-Cell Function in the Development of Diabetes in a Chinese Han Population

Table 1

Clinical characteristics of cases and controls.

Controls ()p-DM () value

Gender (M/F)240/381291/5540.099
Age (y)65.91 ± 7.0761.75 ± 11.3≤0.001
BMI (kg/m2)25.11 ± 3.4326.53 ± 3.77≤0.001
WHR0.87 ± 0.060.89 ± 0.310.041
FPG (mmol/L)5.26 ± 0.425.72 ± 0.57≤0.001
PBG-2h (mmol/L)6.01 ± 1.078.57 ± 1.33≤0.001
TC (mmol/L)5.24 ± 1.005.28 ± 1.110.523
TG (mmol/L)1.54 ± 0.991.86 ± 1.28≤0.001
HDL-C (mmol/L)1.35 ± 0.331.29 ± 0.350.005
LDL-C (mmol/L)3.23 ± 0.943.25 ± 1.500.732

p-DM: prediabetes; BMI: body mass index; WHR: waist-to-hip ratio; FBG: fasting blood glucose; PBG-2h, post-OGTT 2-hour blood glucose; TC: total cholesterol; TG: triglycerides; HDL-C: high-density lipoprotein; LDL-C: low-density lipoprotein.