In Situ Preservation Fraction of Parathyroid Gland in Thyroidectomy: A Cohort Retrospective Study
Table 1
Influence of clinical variables, extent of surgery, and in situ preservation of parathyroid gland on postoperative hypocalcemia and transient and protracted hypoparathyroidism.
Transient hypoparathyroidism
Protracted hypoparathyroidism
Postoperative hypocalcemia
Yes
No
Yes
No
Yes
No
Age
43.48 ± 12.88
43.04 ± 12.84
0.688
40.67 ± 13.53
43.39 ± 12.81
0.259
42.99 ± 12.72
43.47 ± 12.98
0.662
Sex (male/female)
52/208
79/220
0.089
5/25
126/403
0.507
45/217
86/211
0.001
Hypertension
26/234
31/268
>0.999
2/28
55/474
0.758
27/235
30/267
1.000
Diabetes
6/254
6/293
0.774
0/30
12/517
>0.999
9/253
3/294
0.076
HD
71/189
92/207
0.401
8/22
155/374
0.839
78/184
85/212
0.780
Preoperative PTH
5.61 ± 2.94
5.80 ± 2.19
0.386
4.95 ± 0.10
5.75 ± 2.51
0.104
5.55 ± 2.27
5.85 ± 2.79
0.165
Preoperative calcium
2.35 ± 0.40
2.33 ± 0.26
0.555
2.34 ± 0.14
2.34 ± 0.34
0.928
2.32 ± 0.27
2.35 ± 0.38
0.265
Extent of surgery
0.030
0.173
0.981
TTx
3
12
1
14
8
7
TTx + CND
209
246
21
434
212
243
TTx + CND + LND
48
41
8
81
42
47
PGRIF
<0.001
0.022
0.002
0–1/3
21
10
6
25
22
9
1/3–2/3
76
60
8
128
67
69
2/3–1
163
229
20
372
173
219
HD: Hashimoto disease; PTH: parathyroid hormone; TTx: total thyroidectomy; CND: central nodal dissection; LND: lateral nodal dissection; PGRIF: parathyroid gland remaining in situ fraction.