Research Article

In Situ Preservation Fraction of Parathyroid Gland in Thyroidectomy: A Cohort Retrospective Study

Table 1

Influence of clinical variables, extent of surgery, and in situ preservation of parathyroid gland on postoperative hypocalcemia and transient and protracted hypoparathyroidism.

Transient hypoparathyroidismProtracted hypoparathyroidismPostoperative hypocalcemia
YesNoYesNoYesNo

Age43.48 ± 12.8843.04 ± 12.840.68840.67 ± 13.5343.39 ± 12.810.25942.99 ± 12.7243.47 ± 12.980.662
Sex (male/female)52/20879/2200.0895/25126/4030.50745/21786/2110.001
Hypertension26/23431/268>0.9992/2855/4740.75827/23530/2671.000
Diabetes6/2546/2930.7740/3012/517>0.9999/2533/2940.076
HD71/18992/2070.4018/22155/3740.83978/18485/2120.780
Preoperative PTH5.61 ± 2.945.80 ± 2.190.3864.95 ± 0.105.75 ± 2.510.1045.55 ± 2.275.85 ± 2.790.165
Preoperative calcium2.35 ± 0.402.33 ± 0.260.5552.34 ± 0.142.34 ± 0.340.9282.32 ± 0.272.35 ± 0.380.265
Extent of surgery0.0300.1730.981
TTx31211487
TTx + CND20924621434212243
TTx + CND + LND48418814247
PGRIF<0.0010.0220.002
0–1/32110625229
1/3–2/3766081286769
2/3–116322920372173219

HD: Hashimoto disease; PTH: parathyroid hormone; TTx: total thyroidectomy; CND: central nodal dissection; LND: lateral nodal dissection; PGRIF: parathyroid gland remaining in situ fraction.