International Journal of Endocrinology / 2018 / Article / Tab 1

Research Article

A Dipeptidyl Peptidase-4 Inhibitor Suppresses Macrophage Foam Cell Formation in Diabetic db/db Mice and Type 2 Diabetes Patients

Table 1

Characteristics and laboratory data of db/db misty mice and db/db mice at 13 weeks old.

db/db mistydb/db value

Number77
Food intake (g/day)3.1 ± 0.14.5 ± 0.2
Final body weight (g)25.4 ± 0.343.8 ± 0.6
SBP (mmHg)106 ± 4109 ± 40.622
DBP (mmHg)57 ± 361 ± 20.274
Total-C (mg/dL)102 ± 3112 ± 160.473
HDL-C (mg/dL)56 ± 363 ± 130.573
Triglyceride (mg/dL)91 ± 3134 ± 16
Insulin (ng/mL)0.27 ± 0.032.48 ± 0.32
FBG (mg/dL)107 ± 5432 ± 26
HbA1c (%)4.2 ± 0.18.3 ± 0.2
OGTT-AUC (mg/dL × hour)276 ± 31215 ± 85

SBP: systolic blood pressure; DBP: diastolic blood pressure; Total-C: total cholesterol; HDL-C: high-density lipoprotein cholesterol; FBG: fasting blood glucose; HbA1c: hemoglobin A1c; OGTT: oral glucose tolerance test; AUC: area under the curve of glucose. Results are presented as mean values ± SEM and analyzed with unpaired -test. vs. db/db misty mice.

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