Research Article
Triglycerides/Glucose and Triglyceride/High-Density Lipoprotein Cholesterol Indices in Normal and Preeclamptic Pregnancies: A Longitudinal Study
Table 1
Demographic, clinical, and biochemical characteristics of healthy women during pregnancy and three months postpartum.
| Variables | Healthy women () | EP | MP | LP | PP | ANOVA test | Mean ± SD | Mean ± SD | Mean ± SD | Mean ± SD | -value |
| Age (years) | 25.86 ± 5.91 | NA | NA | NA | NA | Gestational age at blood sampling (weeks) | 12.25 ± 0.77 | 24.55 ± 0.67 | 34.73 ± 0.85 | NA | | Height (meters) | 1.58 ± 0.05 | NA | NA | NA | NA | BMI (kg/m2) | 22.7 ± 2.8 | 24.6 ± 2.7 | 26.4 ± 2.8 | 23.69 ± 2.91 | | Systolic blood pressure (mmHg) | 97.7 ± 9.7 | 97.0 ± 10.6 | 99.3 ± 9.3 | 103.22 ± 13.5 | | Diastolic blood pressure (mmHg) | 62.6 ± 6.6 | 61.4 ± 6.4 | 62.4 ± 7.3 | 66.08 ± 9.24 | | Mean blood pressure (mmHg) | 74.3 ± 6.8 | 73.3 ± 7.0 | 74.7 ± 7.2 | 78.67 ± 8.84 | | Fasting glucose (mg/dl) | 77.9 ± 8.1 | 74.1 ± 6.4 | 73.5 ± 6.8 | 80.76 ± 7.43 | | Triglycerides (mg/dl) | 112.0 ± 39.6 | 181.0 ± 58.1 | 236.2 ± 68.9 | 87.44 ± 40.59 | | Total cholesterol (mg/dl) | 165.5 ± 33.1 | 222.1 ± 41.4 | 244.2 ± 49.6 | 170.35 ± 29.9 | | HDL-cholesterol (mg/dl) | 56.0 ± 10.4 | 66.7 ± 12.3 | 64.8 ± 12.8 | 51.12 ± 9.62 | | LDL-cholesterol (mg/dl) | 102.8 ± 31.0 | 138.1 ± 42.4 | 155.4 ± 48.9 | 111.98 ± 32.5 | | C-reactive protein (mg/l) | 5.0 ± 2.9 | 4.8 ± 2.8 | 5.6 ± 3.4 | 3.45 ± 3.40 | | Fasting insulin (μUI/ml) | 8.7 ± 4.0 | 10.7 ± 4.7 | 12.9 ± 4.9 | 8.56 ± 5.15 | | HOMA-IR | 1.69 ± 0.8 | 2.0 ± 0.9 | 2.4 ± 1.0 | 1.73 ± 1.13 | | QUICKI | 0.362 ± 0.03 | 0.352 ± 0.03 | 0.342 ± 0.02 | 0.37 ± 0.04 | | TyG index | 8.3 ± 0.37 | 8.8 ± 0.4 | 9.0 ± 0.3 | 8.08 ± 0.43 | | TG/HDL-c index | 2.1 ± 0.8 | 2.8 ± 1.0 | 3.8 ± 1.2 | 1.80 ± 1.01 | |
|
|
Nonparametric ANOVA test. EP: early pregnancy; MP: middle pregnancy; LP: late pregnancy; PP: three months postpartum; BMI: body mass index; HOMA-IR: homeostasis model assessment-estimated insulin resistance; QUICKI: quantitative insulin sensitivity check index; TyG index: triglycerides/glucose; TG/HDL-c index: triglycerides/high-density lipoprotein cholesterol. A -value < 0.05 was considered statistically significant. |