Research Article

Triglycerides/Glucose and Triglyceride/High-Density Lipoprotein Cholesterol Indices in Normal and Preeclamptic Pregnancies: A Longitudinal Study

Table 1

Demographic, clinical, and biochemical characteristics of healthy women during pregnancy and three months postpartum.

VariablesHealthy women ()
EPMPLPPPANOVA test
Mean ± SDMean ± SDMean ± SDMean ± SD-value

Age (years)25.86 ± 5.91NANANANA
Gestational age at blood sampling (weeks)12.25 ± 0.7724.55 ± 0.6734.73 ± 0.85NA
Height (meters)1.58 ± 0.05NANANANA
BMI (kg/m2)22.7 ± 2.824.6 ± 2.726.4 ± 2.823.69 ± 2.91
Systolic blood pressure (mmHg)97.7 ± 9.797.0 ± 10.699.3 ± 9.3103.22 ± 13.5
Diastolic blood pressure (mmHg)62.6 ± 6.661.4 ± 6.462.4 ± 7.366.08 ± 9.24
Mean blood pressure (mmHg)74.3 ± 6.873.3 ± 7.074.7 ± 7.278.67 ± 8.84
Fasting glucose (mg/dl)77.9 ± 8.174.1 ± 6.473.5 ± 6.880.76 ± 7.43
Triglycerides (mg/dl)112.0 ± 39.6181.0 ± 58.1236.2 ± 68.987.44 ± 40.59
Total cholesterol (mg/dl)165.5 ± 33.1222.1 ± 41.4244.2 ± 49.6170.35 ± 29.9
HDL-cholesterol (mg/dl)56.0 ± 10.466.7 ± 12.364.8 ± 12.851.12 ± 9.62
LDL-cholesterol (mg/dl)102.8 ± 31.0138.1 ± 42.4155.4 ± 48.9111.98 ± 32.5
C-reactive protein (mg/l)5.0 ± 2.94.8 ± 2.85.6 ± 3.43.45 ± 3.40
Fasting insulin (μUI/ml)8.7 ± 4.010.7 ± 4.712.9 ± 4.98.56 ± 5.15
HOMA-IR1.69 ± 0.82.0 ± 0.92.4 ± 1.01.73 ± 1.13
QUICKI0.362 ± 0.030.352 ± 0.030.342 ± 0.020.37 ± 0.04
TyG index8.3 ± 0.378.8 ± 0.49.0 ± 0.38.08 ± 0.43
TG/HDL-c index2.1 ± 0.82.8 ± 1.03.8 ± 1.21.80 ± 1.01

Nonparametric ANOVA test. EP: early pregnancy; MP: middle pregnancy; LP: late pregnancy; PP: three months postpartum; BMI: body mass index; HOMA-IR: homeostasis model assessment-estimated insulin resistance; QUICKI: quantitative insulin sensitivity check index; TyG index: triglycerides/glucose; TG/HDL-c index: triglycerides/high-density lipoprotein cholesterol. A -value < 0.05 was considered statistically significant.