Metabolic Syndrome and Its Components Predict the Risk of Type 2 Diabetes Mellitus in the Mainland Chinese: A 3-Year Cohort Study

Table 2

Multivariate analysis of incident T2DM according to MetS and its components.

Variable	Male		Female
	HR (95% CI)	value	HR (95% CI)	value
Metabolic syndrome	2.68 (2.27, 3.17)	<0.001	2.59 (1.83, 3.65)	<0.001
Overweight	1.76 (1.52, 2.04)	<0.001	1.94 (1.49, 2.52)	<0.001
IGR	3.87 (3.36, 4.46)	<0.001	3.61 (2.87, 4.55)	<0.001
FBG ≥ 6.1 mmol/L	3.12 (2.56, 3.79)	<0.001	3.05 (2.12, 4.38)	<0.001
PG2h ≥ 7.8 mmol/L	3.81 (3.32, 4.39)	<0.001	3.61 (2.87, 4.54)	<0.001
Hypertension	1.63 (1.40, 1.90)	<0.001	1.53 (1.15, 2.02)	0.0030
Dyslipidemia	2.38 (2.07, 2.75)	<0.001	2.18 (1.73, 2.75)	<0.001
TG ≥ 1.7 mmol/L	3.09 (2.66, 3.57)	<0.001	2.98 (2.36, 3.76)	<0.001
Low HDLc	1.19 (0.67, 2.11)	0.5452	1.74 (0.97, 3.10)	0.0619

Data are hazard ratio (95% CI), value. T2DM: type 2 diabetes mellitus; MetS: metabolic syndrome; IGR: impaired glucose regulation; FBG: fasting blood glucose; PG2h: 2-hour postprandial plasma glucose; TG: triglycerides; HDLc: high-density lipoprotein cholesterol. Overweight: defined as BMI greater than 25.0 kg/m²; hypertension: defined as systolic/diastolic blood pressure ≥ 140/90 mmHg or taking antihypertensive agents; low HDL cholesterol: defined as fasting HDL-C < 0.9 or< 1.0 mmol/L in males and females, respectively. Adjusted for age.