Table 1: Change of biochemical parameter during 1 year of antithyroid treatment.

Baseline4 wk8 wk12 wk26 wk52 wk

Free T4 (ng/dL)3.32 ± 1.462.00 ± 0.871.28 ± 0.611.38 ± 0.721.00 ± 0.221.10 ± 0.25
Total T4 (μg/dL)16.0 ± 5.57.6 ± 4.26.2 ± 1.57.8 ± 1.9
Free T3 (ng/dL)2.21 ± 1.630.57 ± 0.470.38 ± 0.080.40 ± 0.13
Total T3 (ng/dL)295 ± 140206 ± 88131 ± 45137 ± 74109 ± 28107 ± 34
TSH (μIU/mL)0.01 ± 0.000.01 ± 0.000.06 ± 0.100.99 ± 0.993.30 ± 5.741.74 ± 1.66
TSH receptor antibody (IU/L)17.99 ± 13.6514.13 ± 13.8712.15 ± 12.7910.97 ± 12.997.65 ± 9.434.43 ± 4.92
Peripheral deiodinase activity (, nmol/s)156 ± 7884 ± 3179 ± 1276 ± 17
Thyroid’s secretory capacity (, pmol/s)623 ± 215165 ± 25995 ± 14276 ± 179
Total cholesterol (mg/dL)158 ± 46210 ± 53203 ± 46221 ± 47
Triglyceride (mg/dL)99 ± 5485 ± 4590 ± 3496 ± 56
HDL cholesterol (mg/dL)48 ± 957 ± 954 ± 1154 ± 11
LDL cholesterol (mg/dL)90 ± 32136 ± 41131 ± 31148 ± 37
AST (IU/L)48 ± 3139 ± 2021 ± 820 ± 7
ALT (IU/L)78 ± 7160 ± 5119 ± 1521 ± 24
ALP (IU/L)101 ± 60118 ± 60106 ± 5162 ± 10

compared to baseline values; peripheral deiodinase activity () and thyroid’ secretory capacity () were calculated with the equations described in Materials and Methods.