Glibenclamide-Induced Autophagy Inhibits Its Insulin Secretion-Improving Function in β Cells

Figure 1

Effect of glibenclamide on insulin secretion in 1640 medium. MIN-6 cells were treated with or without 10 μM glibenclamide in 1640 medium (10 mM glucose) for 4 h. Supernatant was collected, and the insulin level was measured using an ELISA kit. , 1640 vs. 1640 + Glib10. Data shown are mean ± SEM of values from three experiments with triplicate samples.