Dietary Genistein Could Modulate Hypothalamic Circadian Entrainment, Reduce Body Weight, and Improve Glucose and Lipid Metabolism in Female Mice
Dietary genistein could reduce energy intake and body weight in mice fed a high-fat diet. (a) Mean food intake during the experimental period expressed as grams per day; (b) mean energy intake expressed as kcal per day; (c) body weight by the end of the study. CON: normal control diet; HF: high-fat diet without genistein; HFG: high-fat diet with genistein. Data are expressed as means ± S.E.M. (n=8/group). Mean values were significantly different between other groups and the CON group: p<0.05; p<0.01; p<0.001; p<0.0001. Mean values were significantly different between HF group and the HFG group: p<0.05, p<0.01, p<0.001, p <0.0001.