Comparative Proteomic Analysis of Visceral Adipose Tissue in Morbidly Obese and Normal Weight Chinese Women

Figure 2

Volcano plot of the protein differences. The volcano plot illustrates the protein differences. The significantly expressed proteins are located above the horizontal line and on the outer side of the vertical lines. In this volcano plot, the horizontal line represents the 0.05 nominal significance level for protein expression. Vertical lines sort out proteins with at least a twofold difference between morbidly obese and normal weight subjects. Some most significantly changed proteins were identified and named in the figure. Abbreviations: O/N: obese/normal weight; MYH11, myosin-11; UFM1, ubiquitin-fold modifier 1; ACACA, acetyl-CoA carboxylase 1; S100B, protein S100-B; RALY, RNA-binding protein Raly; S100A9, protein S100-A9; H2AFY, core histone macro-H2A; CES1, liver carboxylesterase 1; LCN2, neutrophil gelatinase-associated lipocalin; MB, myoglobin; CTSG, cathepsin G; MMP9, matrix metalloproteinase-9; CKM, creatine kinase M-type; ARG1, arginase-1.