Serum Fibroblast Growth Factor 21 Levels Are Positively Associated with Metabolic Syndrome in Patients with Type 2 Diabetes

Table 2

Odds ratio for metabolic syndrome by multivariable logistic regression analysis of fibroblast growth factor 21 levels among the 126 patients with type 2 diabetes mellitus.

FGF21 (pg/mL)	Unadjusted		Model 1		Model 2		Model 3
	OR (95% CI)	value	OR (95% CI)	value	OR (95% CI)	value	OR (95% CI)	value
Per 1 pg/mL	1.008	0.001	1.007	0.004	1.005	0.027	1.005	0.035
FGF21 increase	(1.003–1.012)		(1.002–1.011)		(1.001–1.010)		(1.000–1.010)

Model 1 is adjusted for age and gender. Model 2 is adjusted for the Model 1 variables and for estimated glomerular filtration rate and urine albumin-to-creatinine ratio. Model 3 is adjusted for the Model 2 variables and for insulin level and homeostasis model assessment of insulin resistance. by multivariate logistic regression analysis. FGF21, fibroblast growth factor 21; OR, odds ratio; CI, confidence interval.