Immunohistochemical Study of NR2C2, BTG2, TBX19, and CDK2 Expression in 31 Paired Primary/Recurrent Nonfunctioning Pituitary Adenomas

Table 2

Noninvasion group versus invasion group and nonrecurrent group versus primary recurrent group.

		Noninvasion	Invasion	X^2	P	Nonrecurrence	Primary recurrence	X^2	P
NR2C2	Low-	26(63.4%)	6(31.6%)	5.287	0.021	32(53.3%)	13(30.2%)	5.433	0.020
	High-	15(36.6%)	13(68.4%)			28(46.7%)	30(69.8%)
BTG2	Low-	35(85.4%)	18(94.7%)	0.384	0.536	53(88.3%)	43(100%)	3.698	0.054
	High-	6(14.6%)	1(5.3%)			7(11.7%)	0(0%)
CDK2	Low-	1(2.4%)	1(5.3%)	-	0.537	2(3.3%)	11(25.6%)	11.242	0.001
	High-	40(97.6%)	18(94.7%)			58(96.7%)	32(74.4%)
TBX19	Low-	31(75.6%)	11(57.9%)	1.940	0.164	42(70.0%)	38(88.4%)	4.875	0.027
	High-	10(24.4%)	8(42.1%)			18(30.0%)	5(11.6%)