Transcriptome Analysis Reveals Significant Differences in Gene Expression of Malignant Pheochromocytoma or Paraganglioma

Table 1

Clinical demographics of malignant and benign PC/PG cases obtained from the TCGA database and the COMETE cohort.

Characteristic	Malignant (n = 30)	Benign (n = 199)	p value
Age (years), mean ± SD	38.9 ± 14.4	43.2 ± 15.7	0.140
Gender, n (%)	30	199	0.432
Male	15 (50.0)	83 (51.1)
Female	15 (50.0)	116 (48.9)
Race, n (%)	11	46	0.497
White	10 (90.9)	36 (78.2)
African-American	1 (9.1)	5 (10.9)
Asia	0 (0)	5 (10.9)
Laterality, n (%)	6	41	0.749
Right	2 (33.3)	19 (46.4)
Left	4 (66.7)	21 (51.2)
Bilaterality	0 (0)	1 (2.4)
Diagnosis, n (%)	30	199	<0.001
PC	15 (50.0)	177 (87.2)
PG	15 (50.0)	22 (12.8)
Size (mm), mean ± SD	73.4 ± 28.1	46.8 ± 20.2	<0.001
Follow-up (days), mean ± SD	2460.2 ± 2658.9	1617.6 ± 867.7	0.320

PC: pheochromocytoma; PG: paraganglioma.