Ginsenoside Rg1 Ameliorates Palmitic Acid-Induced Hepatic Steatosis and Inflammation in HepG2 Cells via the AMPK/NF-B Pathway

Figure 4

G-Rg1 reduces the PA-induced increases in the mRNA and protein expression levels of lipogenic genes. HepG2 cells were treated with 0.25 mM PA for 24 h and then cultivated with 40 or 80 μg/mL G-Rg1 for 6 h. Total proteins were extracted for western blotting (a), quantified by means of the intensities of their bands (b), and total RNA was isolated for qPCR analysis of SREBP-1c and FAS (c). The data represent the means ± SDs of three individual experiments; n=3; P<0.05, P<0.01, P<0.001 (in comparison to the PA-treated model group).

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